ID A5I7G9_CLOBH Unreviewed; 538 AA.
AC A5I7G9; A7G8Q1;
DT 26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Sodium/phosphate cotransporter {ECO:0000313|EMBL:CAL85004.1};
GN OrderedLocusNames=CBO3444 {ECO:0000313|EMBL:CAL85004.1};
OS Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=441771 {ECO:0000313|EMBL:CAL85004.1, ECO:0000313|Proteomes:UP000001986};
RN [1] {ECO:0000313|EMBL:CAL85004.1, ECO:0000313|Proteomes:UP000001986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A [Sanger]
RC {ECO:0000313|Proteomes:UP000001986};
RX PubMed=17519437; DOI=10.1101/gr.6282807;
RA Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA White B., Whithead S., Parkhill J.;
RT "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT Hall A and comparative analysis of the clostridial genomes.";
RL Genome Res. 17:1082-1092(2007).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM412317; CAL85004.1; -; Genomic_DNA.
DR RefSeq; WP_012048348.1; NC_009698.1.
DR RefSeq; YP_001255925.1; NC_009495.1.
DR RefSeq; YP_001389166.1; NC_009698.1.
DR AlphaFoldDB; A5I7G9; -.
DR GeneID; 5186148; -.
DR KEGG; cbh:CLC_3388; -.
DR KEGG; cbo:CBO3444; -.
DR PATRIC; fig|413999.7.peg.3420; -.
DR HOGENOM; CLU_025623_0_1_9; -.
DR Proteomes; UP000001986; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR InterPro; IPR003841; Na/Pi_transpt.
DR InterPro; IPR004633; NaPi_cotrn-rel/YqeW-like.
DR InterPro; IPR038078; PhoU-like_sf.
DR InterPro; IPR026022; PhoU_dom.
DR NCBIfam; NF037997; Na_Pi_symport; 1.
DR NCBIfam; TIGR00704; NaPi_cotrn_rel; 1.
DR PANTHER; PTHR10010:SF46; SODIUM_PHOSPHATE COTRANSPORTER-RELATED; 1.
DR PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR Pfam; PF02690; Na_Pi_cotrans; 2.
DR Pfam; PF01895; PhoU; 2.
DR SUPFAM; SSF109755; PhoU-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001986};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 346..430
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
FT DOMAIN 450..534
FT /note="PhoU"
FT /evidence="ECO:0000259|Pfam:PF01895"
SQ SEQUENCE 538 AA; 58494 MW; 6A998EA55ECA59B0 CRC64;
MNVFAMLTGL IGGLGLFIYG MNLMGDGLQN VAGERVKVFF EKVTSNPIKG VLTGVVVTGV
IQSSSATTVM VVGFVNAGLM TLTQAAGVIM GANIGTTVTG QLVAFNVTAG APLFVGVGTA
IVLFAKKKKT KEIGNIILGF GILFMGMEIM KEAMAPLGQS EAFKSLALSL SHNVFLGIVV
GMGMTAIVQS SSATIGILIA LSSNGVLPLS AALPILFGDN IGTCVTALLA SIGASKNARK
AALFHLTFNV IGTVIFAFIL VPLTPFVRII TNLTPGDVGR QIANAHTLFN LINTFIQIWF
IKYIVAFVNK MIPGSDPYEK MAPKYIDERL LENPTIAINQ TIKEVVRMAN KAKENLQLSI
DAFEKNDLEL VSKVYENEKL INILNKSITT YLVKLNNLKL SDKQLNLVGS MFHVVNDIER
IGDHAENIID LTSEKIEKRI QFSDDAAYDI KHLFNYTLDS LTRTIEGFES NDVERSQSVM
YIEEKIDNLE EQLRETNIKR LNKGTCNANA SAIFLDIINN FERVGDHCTN IAQTVINR
//
