ID A5JJS8_MACMU Unreviewed; 205 AA.
AC A5JJS8;
DT 26-JUN-2007, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2007, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Amelogenin {ECO:0000313|EMBL:ABQ50858.1, ECO:0000313|Ensembl:ENSMMUP00000010818.2};
GN Name=AMELX {ECO:0000313|EMBL:ABQ50858.1,
GN ECO:0000313|Ensembl:ENSMMUP00000010818.2};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:ABQ50858.1};
RN [1] {ECO:0000313|EMBL:ABQ50858.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17645864; DOI=10.1016/j.archoralbio.2007.06.001;
RA Richard B., Delgado S., Gorry P., Sire J.Y.;
RT "A study of polymorphism in human AMELX.";
RL Arch. Oral Biol. 52:1026-1031(2007).
RN [2] {ECO:0000313|EMBL:ABQ50858.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17384026;
RA Delgado S., Ishiyama M., Sire J.Y.;
RT "Validation of amelogenesis imperfecta inferred from amelogenin
RT evolution.";
RL J. Dent. Res. 86:326-330(2007).
RN [3] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [4] {ECO:0000313|EMBL:ABQ50858.1}
RP NUCLEOTIDE SEQUENCE.
RA Sire J.-Y.;
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|Ensembl:ENSMMUP00000010818.2}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000010818.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the amelogenin family.
CC {ECO:0000256|ARBA:ARBA00010383}.
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DR EMBL; EF537871; ABQ50858.1; -; Genomic_DNA.
DR RefSeq; NP_001091983.1; NM_001098513.1.
DR STRING; 9544.ENSMMUP00000010818; -.
DR PaxDb; 9544-ENSMMUP00000010818; -.
DR Ensembl; ENSMMUT00000011539.4; ENSMMUP00000010818.2; ENSMMUG00000008256.4.
DR GeneID; 710057; -.
DR KEGG; mcc:710057; -.
DR CTD; 265; -.
DR VEuPathDB; HostDB:ENSMMUG00000008256; -.
DR eggNOG; ENOG502S4XP; Eukaryota.
DR GeneTree; ENSGT00390000009151; -.
DR OMA; FSYENSY; -.
DR OrthoDB; 4520512at2759; -.
DR TreeFam; TF337092; -.
DR Proteomes; UP000006718; Chromosome X.
DR Bgee; ENSMMUG00000008256; Expressed in cortex of kidney and 8 other cell types or tissues.
DR GO; GO:0062023; C:collagen-containing extracellular matrix; IBA:GO_Central.
DR GO; GO:0030345; F:structural constituent of tooth enamel; IBA:GO_Central.
DR GO; GO:0070166; P:enamel mineralization; IBA:GO_Central.
DR InterPro; IPR004116; Amelogenin.
DR PANTHER; PTHR46794:SF2; AMELOGENIN, X ISOFORM; 1.
DR PANTHER; PTHR46794; AMELOGENIN, Y ISOFORM; 1.
DR Pfam; PF02948; Amelogenin; 1.
DR PRINTS; PR01757; AMELOGENIN.
DR SMART; SM00818; Amelogenin; 1.
PE 3: Inferred from homology;
KW Biomineralization {ECO:0000256|ARBA:ARBA00022591};
KW Reference proteome {ECO:0000313|Proteomes:UP000006718};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..205
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014083831"
FT REGION 109..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..184
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 205 AA; 23099 MW; 7BB5069C9BC93D04 CRC64;
MGTWILFACL LGAAFAMPLP PHPGHPGYIN FSYENSHSQA INVDRTALVL TPLKWYQSIR
PPYPSYGYEP MGGWLHHQII PVLSQQHPPT HTLQPHHHIP VVPAQQPVLP QQPMMPVPGQ
HSMTPTQHHQ PNLPPPAQQP YQPQPVQPQP HQPMQPQPPV HPMQPLPPQP PLPPMFPMQP
LPPMLPDLTL EAWPSTDKTK REEVD
//
