ID A5K0I7_PLAVS Unreviewed; 939 AA.
AC A5K0I7;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=PVX_084470 {ECO:0000313|EMBL:EDL46834.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL46834.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL46834.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL46834.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL46834.1}.
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DR EMBL; AAKM01000002; EDL46834.1; -; Genomic_DNA.
DR RefSeq; XP_001616561.1; XM_001616511.1.
DR AlphaFoldDB; A5K0I7; -.
DR EnsemblProtists; EDL46834; EDL46834; PVX_084470.
DR GeneID; 5475869; -.
DR KEGG; pvx:PVX_084470; -.
DR VEuPathDB; PlasmoDB:PVX_084470; -.
DR InParanoid; A5K0I7; -.
DR OMA; HFQYFIW; -.
DR PhylomeDB; A5K0I7; -.
DR Proteomes; UP000008333; Chromosome 13.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0023051; P:regulation of signaling; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR024162; Adaptor_Cbl.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23007; CBL; 1.
DR PANTHER; PTHR23007:SF11; E3 UBIQUITIN-PROTEIN LIGASE CBL; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT TRANSMEM 377..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 632..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 672..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 863..909
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 111..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..56
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..848
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 939 AA; 107189 MW; 8C935C2F5D88B0CA CRC64;
MHMHAHLSST MTGSKSQMEE EHAPEIAPRE GAKNRKTFRS FHFLKKKNEE RSADNKRNMD
HMFSSSMSYY TSVKDNQKEV INGKGSKLHV RDLEIPNVRV KNKFQFVHVH GAENDSPNPC
LHESSDRGDA ALPHELSGAS DRDRHSAVSG AVSGAGNGAV HGASHNSSNH ASNHVNNHAS
NNPSQNPAQD EDENASLRGD SSAPSTSRRN EEHEESHARG TAIGQETNGQ SLGTISGNVG
EVRNVSRGSG SSGNIPCENA PIENPLSENR VIEGTPPPSG GNIETQNDLL TSMQSQNRNE
AQNDPSRSRN SAENGSNAEE LDYYVLTIRD LRNTHVNESE YENEEGLELA FYQRCFIGKI
LGYEIKPILE EYNLNKAIRL ILFILVMLAL FSMEFALLYN NLLKVRVAEN QFLLIESNYN
NAFLNNFLFQ FNEKELKTWH LTNDMIRDEI TNGNFALHNN MCDVVNKLNV SCDHLLEFYK
SNDEKNKEKI IENSIQLYDE LSKKNMSIYR VKESLLNPCK DISSKTFSGG SNYIFLFVSQ
KKHLKISTLF LILTVFFFCM RIALILSRIL YDFVLFLCFK NYRLSIESKR KYLAKYMWSV
STILFLEIIL GDDCVIWWLH DIDPIFNYHF QYFLWYISLF CLLSYVLHRV FRKYAVRNDS
NNCSSASFSM QYVHDFLFGI NIVFACLFIL LNISKATVIT IIVTDIVLFI DILNDSYLEQ
IRLTNFEEFP SNRQRKKKFY IIENKKKNGK KFTLVRLNEH IYREVTQESN SEKRASKSKG
DLDAGNKGGL KKSCEKKNKI FNLRNVFNKG NIKKKKIPKN VTANGKELEE GNGINSEEEN
HSHVNGDKYD GIDNPGTSSV EYCEICDERF KNVVLYPCMH GGFCETCIRS MIFNSLKLKD
SFPNCPLCRD AIKNVYKISY EDCQKKVQAV TILTIRAKQ
//
