ID A5K2Z9_PLAVS Unreviewed; 1095 AA.
AC A5K2Z9;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=Vacuolar protein sorting-associated protein 52 {ECO:0008006|Google:ProtNLM};
GN ORFNames=PVX_116680 {ECO:0000313|EMBL:EDL45903.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL45903.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL45903.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL45903.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- SIMILARITY: Belongs to the VPS52 family.
CC {ECO:0000256|ARBA:ARBA00008180}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL45903.1}.
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DR EMBL; AAKM01000004; EDL45903.1; -; Genomic_DNA.
DR RefSeq; XP_001615630.1; XM_001615580.1.
DR AlphaFoldDB; A5K2Z9; -.
DR STRING; 126793.A5K2Z9; -.
DR EnsemblProtists; EDL45903; EDL45903; PVX_116680.
DR GeneID; 5474928; -.
DR KEGG; pvx:PVX_116680; -.
DR VEuPathDB; PlasmoDB:PVX_116680; -.
DR InParanoid; A5K2Z9; -.
DR OMA; LINNYCH; -.
DR PhylomeDB; A5K2Z9; -.
DR Proteomes; UP000008333; Chromosome 12.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR007258; Vps52.
DR InterPro; IPR048361; Vps52_C.
DR InterPro; IPR048319; Vps52_CC.
DR PANTHER; PTHR14190; SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52; 1.
DR PANTHER; PTHR14190:SF7; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG; 1.
DR Pfam; PF20655; Vps52_C; 1.
DR Pfam; PF04129; Vps52_CC; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 135..292
FT /note="Vps52 coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF04129"
FT DOMAIN 514..634
FT /note="Vps52 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20655"
FT REGION 43..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 770..889
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 486..502
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..815
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..830
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 831..847
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..882
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1095 AA; 123183 MW; 4E77E67FDDE33007 CRC64;
MQYDRVQALV EQFQEDKYVL RAYGKIYALN RCKAYRSVRV EDVERRRRAS GRGEERPANR
SGEEHPAKGG GEQDANRSGE PPANESAKHA ANRSAKHPAS GKCAAPQLEG LTRIVDETLR
HYTNETLNQF CENDEELARV YSQIDQCSSL CQEVDLVLTN HKNEITCISR DINEIQTLTE
TMNQKLHNRK VTLELLNTYI RIILVTPQLI CAICKGNINE QFIENVKVLT KKLENCKHCS
FDAYPSIRSS HVELLKLKNK AIDRIHRFFL NSINDIQCKR SNVHFVQQHL GRFHELNGFL
YNNCKEIYTH LVKEYVAIMN RTYYNLFRSY LQDLEKKKVV FNGEMTVGGW AGAHEDCAGG
CSDPHSGSSS WQVNWQANRA NLANRANWQT NRSNWQANRA NLASPPGEAG DSLVPGIHAN
LSLLSAKNKM MNMLGFGSRG GAASQDRKES LFPLNGRAGV LLDLAYHPGG GTLSREAFSG
EAPTGEPPIG EPPASKPPTA EPLTAATPPV IFPADDRPHF FEAIYKSVSK LFLDTGTAEY
LFLCNFFRNY ESHEFLFLYV YSKTLSLHFD FLHVYLSDTF DVISLFCIYM INMHNGCLAK
RRGIAPLYEF IHRVQSLVWN RIDYIVGENV KSLATPLEVG RHTPANPPQQ KNHLYHFFHL
NSAQAGSPSS ECASPEGVFT TSAATHLGST DQGEPDEEAI IRNASLQYGS SYEGVTHTNR
HPQSDGTPPH GHTHPVVKRF ADFYCSLVVL TKLSLHFEKQ HHVRMCCGVV SPNEKGSPQG
KKTPPSTTVG APPGEELPHK EEDPISADRD SGKRPNSSDP SGGDLQNVKQ NVKHTIKEKR
RSDKADSQVG LTDGGENPPQ GNRAKDAQHN MEGSPQTAQH TKGDQPVEEK YSHLKDLIGR
LEESIIDVLA VHKNQFAHTR EQLLFLINNY CHVIDVMKRN TIEEEKIERF EALLKKEINA
YVEHQLNHYA TDLILFVCTH EQMVDKLKKD GQHPSDFTSE IDAKLMESVA VQFTTKWKNL
FKNIKQEVTL SFSHTDTSAQ ILKMLNTQIL LYFTRFHQLL KGFFARAQPP PCVQNLPSVD
VVLVQIKRDA KGGDS
//
