ID A5K3M2_PLAVS Unreviewed; 266 AA.
AC A5K3M2;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=CS domain-containing protein {ECO:0000259|PROSITE:PS51203};
GN ORFNames=PVX_117795 {ECO:0000313|EMBL:EDL46126.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL46126.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL46126.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL46126.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- SIMILARITY: Belongs to the p23/wos2 family.
CC {ECO:0000256|ARBA:ARBA00025733}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL46126.1}.
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DR EMBL; AAKM01000004; EDL46126.1; -; Genomic_DNA.
DR RefSeq; XP_001615853.1; XM_001615803.1.
DR AlphaFoldDB; A5K3M2; -.
DR STRING; 126793.A5K3M2; -.
DR EnsemblProtists; EDL46126; EDL46126; PVX_117795.
DR GeneID; 5475151; -.
DR KEGG; pvx:PVX_117795; -.
DR VEuPathDB; PlasmoDB:PVX_117795; -.
DR InParanoid; A5K3M2; -.
DR OMA; TEYDDMA; -.
DR PhylomeDB; A5K3M2; -.
DR Proteomes; UP000008333; Chromosome 12.
DR GO; GO:0051879; F:Hsp90 protein binding; IEA:InterPro.
DR CDD; cd06465; p23_hB-ind1_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR045250; p23-like.
DR PANTHER; PTHR22932:SF1; CO-CHAPERONE PROTEIN DAF-41; 1.
DR PANTHER; PTHR22932; TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE; 1.
DR Pfam; PF04969; CS; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51203; CS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008333}.
FT DOMAIN 2..87
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 185..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..225
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 266 AA; 30162 MW; 091B04FA076A8971 CRC64;
MPLFPIVLWA QKKDCLYLTI ELQDAEDTKI DLKEDKLYFY GKKDKNEYEF TLNFTKPINV
EESKYSTKRN IKFKIIKKEK ERWKTINNDG KKHWVKCDWN SWVDTDEENK TTEYDDMAMN
SFGGMGGMPD MSQFGNMPGM GGLGGMPGMP GMGGMPGMGD LDFSKLGNMG DDMANFSGLG
GMDQFKNMPN MNGMNDDDSS SYGDDTSDDD DEVDDEEEDE DEVDSKNDAD KIHECKDAKC
NMEKDGRHDE EAKIQDPIVE VQEPVA
//
