ID A5K4Q1_PLAVS Unreviewed; 1497 AA.
AC A5K4Q1;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Beige/BEACH domain protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PVX_091820 {ECO:0000313|EMBL:EDL45629.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL45629.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL45629.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL45629.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL45629.1}.
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DR EMBL; AAKM01000005; EDL45629.1; -; Genomic_DNA.
DR RefSeq; XP_001615356.1; XM_001615306.1.
DR STRING; 126793.A5K4Q1; -.
DR EnsemblProtists; EDL45629; EDL45629; PVX_091820.
DR GeneID; 5474652; -.
DR KEGG; pvx:PVX_091820; -.
DR VEuPathDB; PlasmoDB:PVX_091820; -.
DR InParanoid; A5K4Q1; -.
DR OMA; TYMHTIL; -.
DR PhylomeDB; A5K4Q1; -.
DR Proteomes; UP000008333; Chromosome 9.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13743:SF112; BEACH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR Pfam; PF02138; Beach; 1.
DR SMART; SM01026; Beach; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008333}.
FT DOMAIN 346..446
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 454..763
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REGION 274..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 814..917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1046..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1217..1248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..861
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1050..1088
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1497 AA; 168540 MW; 1CC54052C7D5699C CRC64;
MDKSPARCFN LLFLEEDEEY MDDLLVTMRR RQPASIGQHT ASTQPLVAAR GRLRLCSKSL
VFEPYSVEEP VLKFPFKKME NAKMGALGNE IVIKVSEVIK MKTIVHGGKT RCTSQFTYDR
KNRRLLNVMN SLYNEYDEEI RSIDNSTIDQ KIPLFERILS NFDEHEEGSS PAGSKVSGEV
RTSVGDMRAS VGDVRPSVSG GAPFVYFFQC DGAASSAKKL REVYGIMVRI KVAMVVHEKQ
MEILIREKKR KQEGGPSAGG IGAGVGVGVG VVGGEGPLPH HAERDSRHDR GAAAGASPTA
QSPSRSGSQP QNSIKEIHLE KYIERMMEKL TENIKFDISS IGLHERIITN RMEGYWVFKI
SPLLRTKGLL NITNKFIYFQ ANPNFTNKKE KKWKTESILH VFKRIIIMKP NALEIIFDHE
SKKKYSSLYV EFVQYGDREQ IISVLKRINP QCFFIEENKN FVYAIQKKWE GGAISNYEYI
DFINCIAGRS RKDFSQYPVF PWILCDYTRE ELNLNDDSMY RNLRKPVGCL NTDRLNSLIE
KMQDHDYFYG SHYSTLAYVV YFLIRLHPEC QLKLQSGKFD TLSRIFLSIE GTFNTALNAN
SSFIELIPEF YEDNEDFLKN LLNISSNEGN IHDVVLPKWS SSAKDFLTKM KNALESNYAN
KHLNEWINII FGYKQSGQIA KENFNLFHPL TYMHTILNEK LSTANYKSHR ERIRQEEENE
FERNFNEKIK SLITTMPSKA LKTQLHEFGQ CPFQIFREHH VCRKPSVTFR YREDIRNAPW
YYSPVFNQVL RDLFFRRKRR RDLRMRRRLL SRSALGGGAD ASQGEGEDED EEEGEEEEED
EEDDEEEYED DADDDEGEED NYAEQERQRR YDEVGLGGGP PHGAPPGGGA ALPDGAGEEP
LRGKNKRRGP AASAPLAQEV THTKVTHTRR REAETEAYGG EYLQTYQWKL HRSDHFPCVV
KGVGYNQSNV CFVCNNGFIK IITHGDLIRS EMKNNNNLIS LKIGDENFSC VASAQGNYLV
GTSSGNVVLL NPQSILKVNE GGAANSGEAA NSGEAANSGE AANSGEAANS GEAANSGEAA
NSGDCSNTPL SDSSHSLLSS FDDVFEYDAH MGAKKSRGKQ RKSDFLLNAN IYNQMITRKL
HNDTVSSMSF FDSYLATGSA DETVQLLSIE RDFHSLQVYD NFTEAVKFVQ LKNKLLFTHS
DGFKLFDIRV PRRKPLQLGN LNGKRSSPSS GLRASGKFPP RGGSSGNSGS ISALGSGKFF
HLYDNEQVRH FYKTIQKVYE QSYISVNYLT KQYLYEKKMK KNLNQIFLKN FSSIIYSSLV
NDNTVFTLDR DSNLYFYDIR GENWVNVLSK GPTELRRKSS FLIAAGCDDR QQLCAVNTVG
DILFEPINVW NHFNGPVDCP VDCPVDCPVD GPLDGPLDSP LDGPLDGPAA GGLAKTNVFS
SRCSFSPAYI SFINHPDCLG DLAVRGEGGG GNGSCNYILL TGADGRMEIH RRGASWG
//
