ID A5K648_PLAVS Unreviewed; 3410 AA.
AC A5K648;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=CW-type zinc finger domain-containing protein {ECO:0000313|EMBL:EDL45383.1};
GN ORFNames=PVX_090090 {ECO:0000313|EMBL:EDL45383.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL45383.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL45383.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL45383.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL45383.1}.
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DR EMBL; AAKM01000006; EDL45383.1; -; Genomic_DNA.
DR RefSeq; XP_001615110.1; XM_001615060.1.
DR EnsemblProtists; EDL45383; EDL45383; PVX_090090.
DR GeneID; 5474401; -.
DR KEGG; pvx:PVX_090090; -.
DR VEuPathDB; PlasmoDB:PVX_090090; -.
DR InParanoid; A5K648; -.
DR OMA; VQNEKLH; -.
DR PhylomeDB; A5K648; -.
DR Proteomes; UP000008333; Chromosome 5.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.40.100; -; 2.
DR InterPro; IPR042778; ZCWPW1/ZCWPW2.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR15999; UNCHARACTERIZED; 1.
DR PANTHER; PTHR15999:SF2; ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1; 1.
DR Pfam; PF07496; zf-CW; 2.
DR PROSITE; PS51050; ZF_CW; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 13..65
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 722..774
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT REGION 209..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 468..663
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 676..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 784..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 987..1042
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1169..1192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1402..1425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1706..1734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1765..1932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2160..3130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3218..3322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3359..3410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..271
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..426
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..513
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..617
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..655
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..719
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 804..836
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..868
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 869..891
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1403..1425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1792..1816
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1881..1932
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2160..2174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2175..2202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2278..2292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2371..2385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2403..2417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2421..2442
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2476..2496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2513..2541
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2553..2606
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2617..2650
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2658..2697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2711..2750
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2764..2793
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2852..2909
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2916..2977
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2984..3025
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3035..3050
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3087..3130
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3218..3267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3282..3313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3374..3388
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3410 AA; 378594 MW; 1B52701E85BEC112 CRC64;
MINNTKESTD LCTPEQDNWV QCDRCEKWRK LPAYIDMNNL PKIWYCNLNM DTRYNSCDVE
EEVATNNSDL GKHFLAGHLN FAHVAANMER GLHADGAILA EGRSNGVTAI DPSARAHHME
EHFSVGEESF HPSSSHADVP KAYDEPNAFV IKGSHHSNAI RSSSNHVSSN HYSDGKFFSS
LPEKEVPLHG KNIPPVALRN PGAFAFGSSE DVSGPDCEGK NAHMGSNDKR VDGHLGMHTI
QVSTNTKEQR EKEGTMLPKK PLKREEGEKG SGNPRGSNAN RGVAPVPNHV NVNANVNGSY
LKQAKGEDRQ RPPGGKPGNG APNVATKNGK KKNKDTNKGA NKDTNKGANK DTNKGANKDT
TKGTNKGTTK GTSKGANKNA YKNATTKRRK DLLARHKRSN SDGEVYESQR RREECPLHRM
HASDTDMNAA RKVNRYKNFK KNVGSGATPF YSFMHSIVNI NLKYKVKKPS GKEKNKKRGE
EDPPRGISTC EVKEKTEGIG GDGDENRANA PTDKKSAKKK KKKNGDTDQG AASSNVERKK
TQKKKNDRAN GQADGQPNGQ PNGQANPQLK DDPHSAVNRN RGVPHEGGSL QNDNSEKANR
RFIKGEEEAE ERSHLHNGVL SHTNVPQNYM SVPSKSPDLG KNNTPKKEHH DAHFGSAPSN
DQACYTFQAE PNNVVARDAG NSAGGVHPSS SGSQAVNGSN TPIAAKAANS PNAANSPNVA
NSANVVNWVQ CESCKKWRKV DAHINISLLP DEWYCSLNFW SRYNSCSVEE EIYVEENLNS
ELEPSFNQAQ QQGVAVEEES IPLLEGPPKV DKKGKRNEKN QLSERTSKKD HPTKGSALQF
SEKINQAGKG KANKKNRNGN NLIISNGDVT KTREKKNTLP SKANKKAAKG DDSFVENVVS
SNLGHFHSNR FNEYMTNGRD SAARLSGEHE LLDALRTDQF YNPMLKDSYN MPLSCLDVGS
PPFGTSGAEY NSASGGDMLV GFGKRAETQG GKEAKGAKEQ LFNGLPRAAS GSHNRDTRVS
SKRGKSYKRE PQSSSSFLVE KENGSLEGNR FSGNLSAGNP MDLLQGASKY WHLLNNGKLS
YYLNNANIVK MFHSLPKYDY QGNGRDGTVN EEVFPETPLE DQNGGSIGVH SGAHYGAHFG
AHFGAHPAAH LPHYSDLCSE PGKTKRCNSL DVGDRSNGVT PTEANADNPG ERNYLSDSVL
QIRKRKRDFM RKNSEYAYAG GVAKQWHFLH HRSEDNHRGG TIPGDYSSQR YSPSCEGIKS
EYRSSYPGAR PAAYGKRVAG YLSPLARNTH CVNRLEKLNT AVGGYLGGHD EGSGEARGET
NYRENGCEYR FEPRLEHRRG DGPPREDTND EAELCDMLVR RLQSDKYKGT VINRNSVDLG
VGPYGTYGRR GADSDAVEVN YDDNHQHSNT GGGVTKGSAT NPNEDAQMGS NFEGEKIPQI
NRFHHNRAKN NRGDSHYDAV SLTNQLNGEK DETVVSHYLR YSKGGKQEEE LEGMQNYRLS
SANMHNRVGG MDPSCRPFED FKSLPSGVKT NNAFLGSSTT FEGEDKRASQ HSYEMDHLAN
GYPEMYPNQR SSDNHLPRIL KSKSLSNFEK RPYFHLDRSE RSLLPISSSN MSIPKSSSYN
RINSGDYFDL RRGEVASGHY LLKRNAMGSG GDHSMRDIFL SNYYAKLESE KIDTSIKSDM
NKLTSDDYMK IGEYLRRGRR DHATQGDYAC LRSGNKEEEE EEEEGRDIKG SISPSDTSFL
SSSYFSSLPN AYSFDKLMMK IPRSEEMGES NRSHPSEADL GLGYATLPHI PTGTSIPPNE
SKQLKRNAQA SAQKGALKGS FIQGRRDANS RKTAKCATQG KRTSDSKGKN AKMKSNEVGG
VGGVVGGGGG GQPVSASTRR RAADRGPEKD RKSREKQEKQ EKQERLERLE KLDKPEKQEK
QERPGKQDEH NEYITFSMDY NENKNIIKEL IRNRGNLLTG AIPKGSTLSG SYPGGPLPHS
ESAEGGQIKT TILNARNLKK HILSNRVIIY SKGVALAYNV DEINENSIFF YSFEESNITG
NLGNGSPLNG GVTSIVANHN GGGTTNINSS AKYKKSHDDF AKDIQKQAAN NNIYFNYAHN
INFNEKRSAE KSKMKKVTTS VFNYDYKKLI EQVGLFNDSV KLQIPQLKYK FKRYAHLEED
KNDGKKDDEC NATEGGSPHT RSDPSAVNAK LHSVATPSTG STADVKKKEK KKKKEKKEKR
SSPKNGGDDE TDGGESTGEA TGEAAGGGLD GVQLTDYAEG ETPPGRGLLG EDPIGKDLLS
NHPAKKKPTV QKTPEEGPPV GVPAKEEKGS RKAKQSSPLG KKPCRQDAPS GFPSLGETED
AARSSRPGDL APPVSSGSNG ANGNEEACEP GESHVPPKHR DGENTANGWT DPGVKEDSPA
SQPKANKKTS KGVPAERSPT SRETPRNDRS SKEKKPNEKS KKMVPPNAHN NMDEETSVAE
KDNNAVTNEP VAIVGEAEDD PEKRRDLDAP LGRSPKEKGG KKKKAAVRAA RGPARGEQEK
EGQREGQIDD QNGDEVKINP SGKENSRGSN DGKCPPSDEE GEKAAHSNHQ GDTHSEGDMH
EGDPAGKMKN NHKRRQINRT SDLKKEQQPD CLSAPVESSK GRDEDKNDYK GEPKEVQRND
CGREDGSSSA ELLENKTSGD MMEGESETTG DHHKKVHSVE GPPVSVKKKK KNLDSDKDNL
GGTSPPESET NVPTKRRKTA DEHIERPDEK DNKEEKTTPP TDKLAAVKRD SEEEEEEEEE
EEEAKQNCRS KDPDERSSHK KGHSPDRENL KGENNTEGVL WIPLQTEKLL HRRKSRAKKI
IYDDDEDEEC EMSPQKSPNG VPTAAAGEDP RGGNLKNEEV ETDTSCHKEA NKSHPEGVTR
QEESNHPGHR EKGTYRKRKL DEPLKGDSRS SSKGGEQVVH PRDETARLHK VRHSSYSPIR
MADRYDEETQ RRDQKKEHTS MVPKRMQKEE EDNNESPATN KNDSLEEANE RVRPHERGEG
DPRSYNKRAR VHDYKHDRDD TGAWQHNGRG HYAKGGYEQS EERRSVDGRD SRISPSPSVD
RYGDGQSGGH SGGQSGGHSG GHSGGHSGRY SDKHSGGHSG RYSDKHSGWY DGRQSGRNSD
RHSDRHSDKY STWWRDKYSG RYSGRHIDRY GDKHGEKHFE RAGKFVLYAK HHSDMYDRRD
KGYAGHNGNP PRHETYTRHF NDYDHHGRFE KHNSLYEKQD VSGKSDRFDS RANKYNPRSE
RVEETFRRHD GEQFKNVNCE KRHQHTNTTS RNSNRSSLNR TSSHVEDAER KEFPNGSYKR
EREERERLEG RAGEQEGGNY TRYAEKKGRY DYAEGGHHSG YDRGYDRGYD RGYDRGYHGD
HYGHHNHQNH HNHRDHYDHR DHYDHRDRHD RHYHRHGPPS NKLLNKSYQN
//
