ID A5K6U0_PLAVS Unreviewed; 543 AA.
AC A5K6U0;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Glutamine synthetase, putative {ECO:0000313|EMBL:EDL45031.1};
GN ORFNames=PVX_099540 {ECO:0000313|EMBL:EDL45031.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL45031.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL45031.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL45031.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01331, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL45031.1}.
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DR EMBL; AAKM01000007; EDL45031.1; -; Genomic_DNA.
DR RefSeq; XP_001614758.1; XM_001614708.1.
DR AlphaFoldDB; A5K6U0; -.
DR STRING; 126793.A5K6U0; -.
DR EnsemblProtists; EDL45031; EDL45031; PVX_099540.
DR GeneID; 5474049; -.
DR KEGG; pvx:PVX_099540; -.
DR VEuPathDB; PlasmoDB:PVX_099540; -.
DR InParanoid; A5K6U0; -.
DR OMA; PHPHEFE; -.
DR PhylomeDB; A5K6U0; -.
DR Proteomes; UP000008333; Chromosome 7.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:InterPro.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.10.20.70; Glutamine synthetase, N-terminal domain; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR036651; Gln_synt_N_sf.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR PANTHER; PTHR43785; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE; 1.
DR PANTHER; PTHR43785:SF12; GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE PUUA; 1.
DR Pfam; PF00120; Gln-synt_C; 2.
DR Pfam; PF03951; Gln-synt_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF54368; Glutamine synthetase, N-terminal domain; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333}.
FT DOMAIN 112..543
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 543 AA; 61868 MW; C966C5D8D57A7C22 CRC64;
MKPLQFCSAA ELYDFLQDEK NDVEIVACII SNLLGSFFKC FFYVPEISLA KLENGFPFDG
SSIKLCADAE VSDFYIKVDV STCFLESCDG RNMLNVLCDI KRYNGFDYYK CPRTILKKTC
NFVKRENVAD SIFIGNEIEF FIFDKVNFGL DDYDSYLKVY DREAFSCKNG GSGGSAVGSG
SHDTTAGVAC IACAGHVPPN DDSKKVKKKC GYFATDPYDT SNMIKLRICR ILNSLNVHVQ
KYHHEVSTSQ HEISLKYFDA VKNADNLIIT KQVIKSTVHN FNRTATFMPK PLVSDNGSGL
HCNISLWKDN KNIFFADDPS TFFLSKEAFY FMNGIIKHAK ALQAFCNSTM NSYKRLVPGF
ETCQKLFYSF GSRNAVIRLS MINYSNPSEK RIEFRLPDYA NSPHLVLAAI ILAGYDGIKS
KEQPLVPFES KDNNFFISSI FSNYVENTQN FKTLTHALEG YDTIHDVKKS PEFVNFFTCK
EPESICFSLE ESLDALEKDH AFLTVDGIFT EEVIEEYIKF KRDEIAAYRR KVTPYDYYLY
YDC
//
