ID A5K6U9_PLAVS Unreviewed; 277 AA.
AC A5K6U9;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Cyclin-dependent kinases regulatory subunit {ECO:0000256|RuleBase:RU311113};
GN ORFNames=PVX_099585 {ECO:0000313|EMBL:EDL45040.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL45040.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL45040.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL45040.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- FUNCTION: Binds to the catalytic subunit of the cyclin dependent
CC kinases and is essential for their biological function.
CC {ECO:0000256|RuleBase:RU311113}.
CC -!- SIMILARITY: Belongs to the CKS family. {ECO:0000256|RuleBase:RU311113}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL45040.1}.
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DR EMBL; AAKM01000007; EDL45040.1; -; Genomic_DNA.
DR RefSeq; XP_001614767.1; XM_001614717.1.
DR AlphaFoldDB; A5K6U9; -.
DR STRING; 126793.A5K6U9; -.
DR EnsemblProtists; EDL45040; EDL45040; PVX_099585.
DR GeneID; 5474058; -.
DR KEGG; pvx:PVX_099585; -.
DR VEuPathDB; PlasmoDB:PVX_099585; -.
DR InParanoid; A5K6U9; -.
DR OMA; SGHDDYY; -.
DR PhylomeDB; A5K6U9; -.
DR Proteomes; UP000008333; Chromosome 7.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.170.10; Cyclin-dependent kinase, regulatory subunit; 1.
DR InterPro; IPR000789; Cyclin-dep_kinase_reg-sub.
DR InterPro; IPR036858; Cyclin-dep_kinase_reg-sub_sf.
DR Pfam; PF01111; CKS; 1.
DR SMART; SM01084; CKS; 1.
DR SUPFAM; SSF55637; Cell cycle regulatory proteins; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|RuleBase:RU311113};
KW Cell division {ECO:0000256|RuleBase:RU311113};
KW Reference proteome {ECO:0000313|Proteomes:UP000008333}.
FT REGION 1..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 277 AA; 29837 MW; 29B0ECC6EEE9A8E1 CRC64;
MNRPGGTPLN RSSREKSNEK NGAKSASKGV RRSSGKGISK GSRKSGAVGS GVGSGVSNDV
SSSISSRANA TTDRTTNRST DEGADNPAGS SPKSAANNPA GSSPKSAANN PAGSSPKSAA
NNPAGSSPKS AANNSGHDDY YAILEELAKS ETPKFRSVQD SMDENLNLEF LRSSSENYTY
KITSRGPVCY SALYRDDKYV YRHIILSDNV RQYAESKVRK TNAFLTEHCI VNELQIDIGK
GWKHFMIYDG KIRELILRKV LTAEDKLRMA VQAQKYN
//
