ID A5KAG0_PLAVS Unreviewed; 393 AA.
AC A5KAG0;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=HTH TFE/IIEalpha-type domain-containing protein {ECO:0000259|PROSITE:PS51344};
GN ORFNames=PVX_000565 {ECO:0000313|EMBL:EDL43559.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL43559.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL43559.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL43559.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- SIMILARITY: Belongs to the TFIIE alpha subunit family.
CC {ECO:0000256|ARBA:ARBA00008947}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL43559.1}.
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DR EMBL; AAKM01000015; EDL43559.1; -; Genomic_DNA.
DR RefSeq; XP_001613286.1; XM_001613236.1.
DR AlphaFoldDB; A5KAG0; -.
DR STRING; 126793.A5KAG0; -.
DR EnsemblProtists; EDL43559; EDL43559; PVX_000565.
DR VEuPathDB; PlasmoDB:PVX_000565; -.
DR InParanoid; A5KAG0; -.
DR OMA; FMELQDE; -.
DR PhylomeDB; A5KAG0; -.
DR Proteomes; UP000008333; Chromosome 3.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039997; TFE.
DR InterPro; IPR017919; TFIIE/TFIIEa_HTH.
DR InterPro; IPR002853; TFIIE_asu.
DR InterPro; IPR024550; TFIIEa/SarR/Rpc3_HTH_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13097:SF7; GENERAL TRANSCRIPTION FACTOR IIE, POLYPEPTIDE 1, ALPHA; 1.
DR PANTHER; PTHR13097; TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT; 1.
DR Pfam; PF02002; TFIIE_alpha; 1.
DR SMART; SM00531; TFIIE; 1.
DR PROSITE; PS51344; HTH_TFE_IIE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008333};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..114
FT /note="HTH TFE/IIEalpha-type"
FT /evidence="ECO:0000259|PROSITE:PS51344"
FT REGION 205..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..325
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 393 AA; 45551 MW; 9DF89E71729C1B04 CRC64;
MEKSKEIFYD KEKRFFLHLM MYVSRFFLND EEIVIFDLFV HNECLYLEKD IINSINMHEQ
KIRSILSKLL KEKFIIQVQK LKTTERGSSF QMYYCLNNYI VYVIDYRVRR MEVELRKDRN
DSDLYVCTFC NATYSQLDAQ LLPLDSYDAH FLCLCNNKIQ LVERDESSDE RIYSRYTKYL
DILKEHTEKL KNYFIPLYTE KFSRVAPSST HSPPADHSSD ESLTNNSSEL SLTNNSSLVS
QNNPGRAAEQ RKATNEETPT DACSSVIRSD KKIKICMNVK GKKGSIQVAS PSSGGRAANP
GKGEAEESTE QKGHTTGRTK HKSGDLAHAQ QSASEMAVLK DAQKADEPEM PLFFIEKFNK
EFSLMDAQKL QQDMTQDEFE RFMELQDEYL DLI
//
