ID A5KDX6_PLAVS Unreviewed; 1099 AA.
AC A5KDX6;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE SubName: Full=Asparagine-rich antigen, putative {ECO:0000313|EMBL:EDL42425.1};
GN ORFNames=PVX_111120 {ECO:0000313|EMBL:EDL42425.1};
OS Plasmodium vivax (strain Salvador I).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=126793 {ECO:0000313|EMBL:EDL42425.1, ECO:0000313|Proteomes:UP000008333};
RN [1] {ECO:0000313|EMBL:EDL42425.1, ECO:0000313|Proteomes:UP000008333}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Salvador I {ECO:0000313|EMBL:EDL42425.1,
RC ECO:0000313|Proteomes:UP000008333};
RX PubMed=18843361; DOI=10.1038/nature07327;
RA Carlton J.M., Adams J.H., Silva J.C., Bidwell S.L., Lorenzi H., Caler E.,
RA Crabtree J., Angiuoli S.V., Merino E.F., Amedeo P., Cheng Q., Coulson R.M.,
RA Crabb B.S., Del Portillo H.A., Essien K., Feldblyum T.V.,
RA Fernandez-Becerra C., Gilson P.R., Gueye A.H., Guo X., Kang'a S.,
RA Kooij T.W., Korsinczky M., Meyer E.V., Nene V., Paulsen I., White O.,
RA Ralph S.A., Ren Q., Sargeant T.J., Salzberg S.L., Stoeckert C.J.,
RA Sullivan S.A., Yamamoto M.M., Hoffman S.L., Wortman J.R., Gardner M.J.,
RA Galinski M.R., Barnwell J.W., Fraser-Liggett C.M.;
RT "Comparative genomics of the neglected human malaria parasite Plasmodium
RT vivax.";
RL Nature 455:757-763(2008).
CC -!- SIMILARITY: Belongs to the DCP1 family.
CC {ECO:0000256|ARBA:ARBA00008778}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDL42425.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAKM01002769; EDL42425.1; -; Genomic_DNA.
DR RefSeq; XP_001608449.1; XM_001608399.1.
DR AlphaFoldDB; A5KDX6; -.
DR STRING; 126793.A5KDX6; -.
DR EnsemblProtists; EDL42425; EDL42425; PVX_111120.
DR GeneID; 5471413; -.
DR KEGG; pvx:PVX_111120; -.
DR VEuPathDB; PlasmoDB:PVX_111120; -.
DR InParanoid; A5KDX6; -.
DR OMA; HNEANIY; -.
DR PhylomeDB; A5KDX6; -.
DR Proteomes; UP000008333; Chromosome 6.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR CDD; cd09804; Dcp1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010334; Dcp1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR16290:SF0; DECAPPING PROTEIN 1, ISOFORM A; 1.
DR PANTHER; PTHR16290; TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1; 1.
DR Pfam; PF06058; DCP1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008333}.
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..1041
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 971..1013
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1016..1041
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1099 AA; 116415 MW; C22A5B688F120326 CRC64;
MKKKNIAAAT SYGKVKSRVN RYDMNGSYNF NETKNGGKVP GGGTPGDGKK SRPEAPPAGK
AANSAVTSPQ NSGGGNAHHA QAAKYVKNAY PYDYNAYGPK KVGEYKEKMK GPMKGAGHGG
DGGAHGEGRS SQAGMNSGGA PDGKAIAGGS KGNVDDANGA NMNGGNANGG NTTGVHPSGA
NLSNTNAGRS QNTGRKGNKN ENLNEEVSLL REKICFKMLK SIDIYITEII MKSSFVTVYK
MKEDELKWVR ADIEGFLYIV RRSIKPTYRL IITNKKNENH LVQDIHGRIN LSTDQNYIFY
RVHNEESNLK STYSLWFYST EEKEKIYSML RELVDRGAGA PSVSGAANLG SSDVSGIANG
ANVGYVHSKN INFILSKGEG GVSEGAAIGG MAVGGMAAGG MTTGGMAAGG VAPGGGIMGA
NPNDSSSKSV LLNGHDEELL KGGAISGADH AQRKANAKNG IPMMAPDSGR DNDYEKNFEL
MGNNKLENLY AKMNIPLGEG GHIPPGAANA IYGNYLKQLY KSSGGVNGMD GMEAIGQRGK
MKDTPGEEGL AGCDSNVKGG AQQNSVDFND KVGRKLLYLI KGLPMEGERG VEKGGERGGE
KGSDNLKKLS GPDFYEGRKS EDMPRGGGGG TNNPAVDPKG GGGGGGYPND KGSAISGGEA
IMNLLGLSKN SDVKEDEVED KKKKKKKKGA SGEGPSGGGA NGSANGNAAA IAIVNANASS
GAITSGDNAG MNQMGSALGA KGFEANMQKR GLQLREMQLR ELQFREMQLR EMQLRGMQMN
GLVMNGVPIN GMAMNGMLPS GMPPNGMLPN GVPPNGMPPN GMPPNLMQMH HPQGNDLQML
PLPAEEMNGK AMKYAKGKSD CSEEPVSNNH PVEKAYLERP SFQNNSIESL HSKEVEVING
NMDDEKQMTS ALLNIIKQKG DRANHVQGFE GANHHGGHDG MNEFHPDSYE MLLKMQGGGG
SGERRAKSGQ RVTNRMGSHV GSQLGSQLGS HLGSHLGSNL GSHLGSHLGS HLDNRSHNGP
FDEGEMPRRN NHPGYSPHDK QLLKYEDERM DSFSGVEDYK NRSILLSRNT IHNVIKETLQ
SDEFVNLLWE KLVTSKNIM
//
