ID A5LGH1_CRAGI Unreviewed; 280 AA.
AC A5LGH1;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 13-SEP-2023, entry version 63.
DE SubName: Full=Voltage-dependent anion channel {ECO:0000313|EMBL:BAF63641.1};
DE SubName: Full=Voltage-dependent anion-selective channel protein 2 {ECO:0000313|EMBL:EKC43202.1};
GN Name=VDAC {ECO:0000313|EMBL:BAF63641.1};
GN ORFNames=CGI_10027300 {ECO:0000313|EMBL:EKC43202.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:BAF63641.1};
RN [1] {ECO:0000313|EMBL:BAF63641.1}
RP NUCLEOTIDE SEQUENCE.
RA Yokoyama Y.;
RT "cDNA cloning and expression of oyster voltage-dependent anion channel.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EKC43202.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC43202.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SIMILARITY: Belongs to the eukaryotic mitochondrial porin family.
CC {ECO:0000256|ARBA:ARBA00007780}.
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DR EMBL; AB262088; BAF63641.1; -; mRNA.
DR EMBL; JH817465; EKC43202.1; -; Genomic_DNA.
DR RefSeq; NP_001292225.1; NM_001305296.1.
DR AlphaFoldDB; A5LGH1; -.
DR SMR; A5LGH1; -.
DR GeneID; 105339176; -.
DR KEGG; crg:105339176; -.
DR HOGENOM; CLU_044399_2_0_1; -.
DR InParanoid; A5LGH1; -.
DR OrthoDB; 2897965at2759; -.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-KW.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0008308; F:voltage-gated monoatomic anion channel activity; IEA:InterPro.
DR CDD; cd07306; Porin3_VDAC; 1.
DR Gene3D; 2.40.160.10; Porin; 1.
DR InterPro; IPR023614; Porin_dom_sf.
DR InterPro; IPR001925; Porin_Euk.
DR InterPro; IPR027246; Porin_Euk/Tom40.
DR PANTHER; PTHR11743:SF70; GH26960P-RELATED; 1.
DR PANTHER; PTHR11743; VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL; 1.
DR Pfam; PF01459; Porin_3; 1.
DR PRINTS; PR00185; EUKARYTPORIN.
DR PROSITE; PS00558; EUKARYOTIC_PORIN; 1.
PE 2: Evidence at transcript level;
KW Ion transport {ECO:0000256|ARBA:ARBA00023114};
KW Membrane {ECO:0000256|ARBA:ARBA00022452};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Porin {ECO:0000256|ARBA:ARBA00023114};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022452};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00023114}.
SQ SEQUENCE 280 AA; 30329 MW; 52E25355933BC94A CRC64;
MAPPTYGDLG KAAKDIFSKG YNYGEWKLEA KTKTDSGVEF TTTGSHSDKG IISGSLETKY
KYSDLGLTFK EKWNTSNVLF TEIAIEDQLV KGLKLEFNTS FAPQTGTKSG KIKTSYKMDY
LNLGCDVDFV FAGPTINAAA VLGYKGWLGG YQMSFDTSKS KLTKNNFAVG YEASDFTIHT
NVNDGAEYCG SIYHKIRKDL EGGVKLSWSS AKSTALELGT KYKIDSDSSV SAKVDSNSRV
GLGYTTKLRD GVKLTLSALV DGKNFNAGGH QLGLGLDFEA
//
