GenomeNet

Database: UniProt
Entry: A5MZ70_CLOK5
LinkDB: A5MZ70_CLOK5
Original site: A5MZ70_CLOK5 
ID   A5MZ70_CLOK5            Unreviewed;       679 AA.
AC   A5MZ70;
DT   10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   10-JUL-2007, sequence version 1.
DT   08-MAY-2019, entry version 77.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   OrderedLocusNames=CKL_2154 {ECO:0000313|EMBL:EDK34166.1};
OS   Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=431943 {ECO:0000313|EMBL:EDK34166.1, ECO:0000313|Proteomes:UP000002411};
RN   [1] {ECO:0000313|EMBL:EDK34166.1, ECO:0000313|Proteomes:UP000002411}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8527 / DSM 555 / NCIMB 10680
RC   {ECO:0000313|Proteomes:UP000002411};
RX   PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA   Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA   Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA   Hagemeier C., Thauer R.K., Gottschalk G.;
RT   "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT   metabolic features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000673; EDK34166.1; -; Genomic_DNA.
DR   RefSeq; WP_012102493.1; NC_009706.1.
DR   STRING; 431943.CKL_2154; -.
DR   EnsemblBacteria; EDK34166; EDK34166; CKL_2154.
DR   KEGG; ckl:CKL_2154; -.
DR   eggNOG; ENOG4105CE1; Bacteria.
DR   eggNOG; COG0370; LUCA.
DR   HOGENOM; HOG000054021; -.
DR   KO; K04759; -.
DR   OMA; EALAFMF; -.
DR   OrthoDB; 304844at2; -.
DR   BioCyc; CKLU431943:GJF1-2147-MONOMER; -.
DR   Proteomes; UP000002411; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002411};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002411};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    289    315       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    335    368       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    422    440       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    446    469       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    517    534       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    554    572       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    579    599       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    623    644       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    656    678       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        3    165       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   679 AA;  74622 MW;  B7BB0E6F9C02ED4A CRC64;
     MSSTTIALLG QPNSGKSTLF NALTGSHQHV GNWPGKTVEQ KEGYFTYHNK KYTIVDLPGT
     YSLSANSEEE IVTREYISSG KAELVCILAD ASQLQRSLFM LADYAGIKTP VVLLLNMMDI
     AQQQGKNINS AAISKELGIP VVPIVAADKK CYDDFFKVLE KIQEIQGVLD EKDILNLYTV
     TIGNRYKQIL QLLPEEGIDT YSSAWLASKL VEQDSMAVNV VKSYVSDDTW GRISLILEQV
     KNGSLLTGEC KFRWIENLLK YNVSEGKTRE PKIGFFDRIA TSKTWGKPLA IGIIILGLIL
     SMAIAMPFMS LFGYFPNIFY DPISKGLFYM GMPSVIISLL CDGVITAISF ALMMVSFVFG
     ISLVFGFLEE VGYMARISYV FDNTMSKLGL QGKAVMPFLV SFGCNIGGVS GTRVIDSWGQ
     RVITMALSWV IPCAATWGVV GLMSSVFFGG GAVFVIISLF AVALLHMIVT SKIFGKSLIK
     ESDRSGLIME LPPYHKPKYK NLFRFVFNRM SDVLKRALKI IVLVSVFFWA LSYTPDGNVT
     DSIIYKVGTF IEPVTMWFGL RWQTFMAFIA SAMGKEAALG VLASLFNSSG AVAGIWGSIS
     GKAAVNTSGL AGALISGISK AEALAFIYAF FFNVPCIMAV ASTQQESHSI KWTLRIVGYY
     IVVALIMSFI AYHIGLFIF
//
DBGET integrated database retrieval system