ID A5N1R7_CLOK5 Unreviewed; 402 AA.
AC A5N1R7;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Predicted transcriptional regulator {ECO:0000313|EMBL:EDK35063.1};
GN OrderedLocusNames=CKL_3055 {ECO:0000313|EMBL:EDK35063.1};
OS Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=431943 {ECO:0000313|EMBL:EDK35063.1, ECO:0000313|Proteomes:UP000002411};
RN [1] {ECO:0000313|EMBL:EDK35063.1, ECO:0000313|Proteomes:UP000002411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8527 / DSM 555 / NCIMB 10680
RC {ECO:0000313|Proteomes:UP000002411};
RX PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA Hagemeier C., Thauer R.K., Gottschalk G.;
RT "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT metabolic features.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
CC -!- FUNCTION: Transcriptional repressor of xylose-utilizing enzymes.
CC {ECO:0000256|ARBA:ARBA00002486}.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; CP000673; EDK35063.1; -; Genomic_DNA.
DR RefSeq; WP_012103398.1; NC_009706.1.
DR AlphaFoldDB; A5N1R7; -.
DR STRING; 431943.CKL_3055; -.
DR KEGG; ckl:CKL_3055; -.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_1_9; -.
DR Proteomes; UP000002411; Chromosome.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF13412; HTH_24; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002411}.
SQ SEQUENCE 402 AA; 44527 MW; D9EAB165C7209A08 CRC64;
MKDNSNALKS LSFEEKKIFN LLQKNGRLSK NKISSRTDIK LTTLNYVMEP LEKSKMIVES
CIGESTGGRR PILYDININD FYIIGIDISI LYTQVVITNL KMEILYKELF NMDDSYTPCE
TVKKVVEIIN RAYANLNLSH MKLLGIGVGS VGPLDIKNGI IKNPVDFFAD KWTDVPIKKM
LEEKLKHPVI VENGANAAVV AEYFYGVGRG IENIAFFNCG IGIRTGTISS GHLIRTINDE
EEAFGHMTID IDGEKCKCGN YGCLECYSTI KAIIKNISKK IKKGRHTIIN KPVEEIDYKD
VCLAAEMGDE LSIDIITDAA LILGSGLSNY IKLLSPKLVI LTGPLIINSK LFYEVCVKST
LKNLNSTKGK SVIFNRCGYF SGDAISIGAS AMVIERCLES GI
//
