ID   A5N870_CLOK5            Unreviewed;       205 AA.
AC   A5N870;
DT   10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   10-JUL-2007, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=Predicted hydrolase {ECO:0000313|EMBL:EDK33501.1};
GN   OrderedLocusNames=CKL_1459 {ECO:0000313|EMBL:EDK33501.1};
OS   Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=431943 {ECO:0000313|EMBL:EDK33501.1, ECO:0000313|Proteomes:UP000002411};
RN   [1] {ECO:0000313|EMBL:EDK33501.1, ECO:0000313|Proteomes:UP000002411}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8527 / DSM 555 / NCIMB 10680
RC   {ECO:0000313|Proteomes:UP000002411};
RX   PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA   Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA   Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA   Hagemeier C., Thauer R.K., Gottschalk G.;
RT   "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT   metabolic features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
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DR   EMBL; CP000673; EDK33501.1; -; Genomic_DNA.
DR   RefSeq; WP_012101851.1; NC_009706.1.
DR   AlphaFoldDB; A5N870; -.
DR   STRING; 431943.CKL_1459; -.
DR   KEGG; ckl:CKL_1459; -.
DR   eggNOG; COG0494; Bacteria.
DR   HOGENOM; CLU_040940_5_2_9; -.
DR   Proteomes; UP000002411; Chromosome.
DR   GO; GO:0010945; F:coenzyme A diphosphatase activity; IEA:InterPro.
DR   CDD; cd03426; CoAse; 1.
DR   Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR   InterPro; IPR045121; CoAse.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   PANTHER; PTHR12992:SF11; MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8; 1.
DR   PANTHER; PTHR12992; NUDIX HYDROLASE; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   SUPFAM; SSF55811; Nudix; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EDK33501.1};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002411}.
FT   DOMAIN          20..152
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000259|PROSITE:PS51462"
SQ   SEQUENCE   205 AA;  24170 MW;  C666CE431962832E CRC64;
     MIKKIEDIFK ERKPHIMGEF SKSAVMIPLC ESGEEISVLF EMRALNLKHQ PGDICFPGGR
     LEKGEIPVCA AVRETMEELN LSKEDIKLIG QMDYVVTPYN FIMYPFVCKL NREDIFPSQS
     EVDHIFKVPL QFFIENKPLL YEIPIVSQPG KRFPYRLIRN GRKYKFRRGT VKQYFYNYEK
     YTIWGFTALI IKRFVDIIVS NDHNK
//