ID   A5P6N6_9SPHN            Unreviewed;       653 AA.
AC   A5P6N6;
DT   10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   10-JUL-2007, sequence version 1.
DT   24-JAN-2024, entry version 57.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN   ORFNames=ED21_25988 {ECO:0000313|EMBL:EDL49987.1};
OS   Erythrobacter sp. SD-21.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Erythrobacteraceae; Erythrobacter/Porphyrobacter group; Erythrobacter.
OX   NCBI_TaxID=161528 {ECO:0000313|EMBL:EDL49987.1, ECO:0000313|Proteomes:UP000005498};
RN   [1] {ECO:0000313|EMBL:EDL49987.1, ECO:0000313|Proteomes:UP000005498}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SD-21 {ECO:0000313|EMBL:EDL49987.1,
RC   ECO:0000313|Proteomes:UP000005498};
RA   Tebo B., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDL49987.1}.
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DR   EMBL; ABCG01000001; EDL49987.1; -; Genomic_DNA.
DR   RefSeq; WP_006831801.1; NZ_ABCG01000001.1.
DR   AlphaFoldDB; A5P6N6; -.
DR   STRING; 161528.ED21_25988; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG5616; Bacteria.
DR   Proteomes; UP000005498; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005498}.
FT   DOMAIN          4..89
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
SQ   SEQUENCE   653 AA;  72803 MW;  9F9421B4205AB6A9 CRC64;
     MAEIFISYAR STADQAQAAA RGLREEGYEV WIDDALPAHR EFSVVIEEKL QEVDAVLVVW
     SEDARRSRWV LAEADLAHEQ GKLVQFSLDG TIPPFPFNRV HCEQGIGWSG DITAAPWRKI
     VASVEELSGG GDDTLAGIGP EFTRPTSREP LLAVMAFDNF SADAELDFFC DGISEEIQRT
     VASGSSLKVV ARASSFQFRG SAKDTARVAS ALGATHLLDG SVRRAQNRVR ISAELVECTT
     RSAIWADRFD GDLDDVFDLQ ERIAEKVAEA LKVALVPTRK EEALDPASYE AYMRARGIMA
     EGDPLFDDAY RESIPLLERV VAAAPNFAAA WESLAECRAW TLRSGRYDKA YHIGRDGVID
     AARTALRLDP KSGGAYVALA MLEPWGAYSQ REALLRKALE VSPRDTAALT DMSTFCWSVG
     RFRDGLRYAE RACELNPLMP SARLNVAQMR AYVGDIDICV AMHEQLHRQW PDNPGILISL
     VNTAGTLGYW DAFDRAVPDV GQLNEWQSRD MRAALAFAQA VRTKDPELIE RRMTRYREYL
     DKTGHLPLNL VVSIGEFGLA NEALDMAERA SYDFVFNPDG ARPSAYFPGT IMGPWSKVLQ
     QPRFVDLCTR LGMSEYWQST GKWPDCEEWV EYDFRAEVER SLAEAQREKI PAP
//