ID A5PJY3_BOVIN Unreviewed; 297 AA.
AC A5PJY3;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=MCART1 protein {ECO:0000313|EMBL:AAI42285.1};
DE SubName: Full=Solute carrier family 25 member 51 {ECO:0000313|Ensembl:ENSBTAP00000019883.4};
GN Name=MCART1 {ECO:0000313|EMBL:AAI42285.1};
GN Synonyms=SLC25A51 {ECO:0000313|Ensembl:ENSBTAP00000019883.4};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI42285.1};
RN [1] {ECO:0000313|EMBL:AAI42285.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hereford {ECO:0000313|EMBL:AAI42285.1};
RC TISSUE=Hypothalamus {ECO:0000313|EMBL:AAI42285.1};
RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A.,
RA Holt R., Jones S.J., Marra M.A.;
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000019883.4, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000019883.4,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000019883.4}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000019883.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; BC142284; AAI42285.1; -; mRNA.
DR RefSeq; NP_001092864.1; NM_001099394.1.
DR RefSeq; XP_005210234.1; XM_005210177.3.
DR RefSeq; XP_005210235.1; XM_005210178.3.
DR RefSeq; XP_005210236.1; XM_005210179.3.
DR RefSeq; XP_005210238.1; XM_005210181.3.
DR RefSeq; XP_005210239.1; XM_005210182.3.
DR RefSeq; XP_005210240.1; XM_005210183.3.
DR RefSeq; XP_015328032.1; XM_015472546.1.
DR STRING; 9913.ENSBTAP00000019883; -.
DR PaxDb; 9913-ENSBTAP00000019883; -.
DR Ensembl; ENSBTAT00000019883.5; ENSBTAP00000019883.4; ENSBTAG00000014936.5.
DR GeneID; 781425; -.
DR KEGG; bta:781425; -.
DR CTD; 92014; -.
DR VEuPathDB; HostDB:ENSBTAG00000014936; -.
DR eggNOG; KOG1519; Eukaryota.
DR GeneTree; ENSGT00940000155622; -.
DR HOGENOM; CLU_061821_0_0_1; -.
DR OMA; GCAFNTG; -.
DR OrthoDB; 46552at2759; -.
DR TreeFam; TF314192; -.
DR Proteomes; UP000009136; Chromosome 8.
DR Bgee; ENSBTAG00000014936; Expressed in oocyte and 107 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0051724; F:NAD transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1990549; P:mitochondrial NAD transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR46131:SF2; MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER SLC25A51; 1.
DR PANTHER; PTHR46131; SD08549P; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT TRANSMEM 172..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 28..108
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 116..200
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 213..296
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 297 AA; 33957 MW; 9B43B4421446C59C CRC64;
MMDSEAHEKR PPILTSSKQD IAPHIATVSE MKHYLCGCCA AFNNIAITFP IQKVLFRQQL
YGIKTRDAIL QLRRDGFRNL YRGILPPLMQ KTTTLALMFG LYEDLSCLLR KHVSTPEFAT
RSMAAVLAGT TEAIFTPLER VQTLLQDHRH HDKFTNTYQA FKALKCHGIR EYYRGLVPVL
FRNGFSNVLF FGLRGPIKEH LPTATTHSAH LVNDFICGGL LGAMLGILFF PVNVVKTRMQ
SQIGGEFQSF PKVFQKIWLE RDRKLTNLFR GAHLNYHRSL ISWGIINATY EFLLKII
//
