ID   LR2BP_DANRE             Reviewed;         343 AA.
AC   A5PLI4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=LRP2-binding protein;
GN   Name=lrp2bp; ORFNames=zgc:165631;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as an adapter that regulates LRP2 function.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; BC142915; AAI42916.1; -; mRNA.
DR   RefSeq; NP_001092246.1; NM_001098776.1.
DR   AlphaFoldDB; A5PLI4; -.
DR   SMR; A5PLI4; -.
DR   STRING; 7955.ENSDARP00000134329; -.
DR   PaxDb; 7955-ENSDARP00000059242; -.
DR   PeptideAtlas; A5PLI4; -.
DR   GeneID; 100073340; -.
DR   KEGG; dre:100073340; -.
DR   AGR; ZFIN:ZDB-GENE-070615-41; -.
DR   CTD; 55805; -.
DR   ZFIN; ZDB-GENE-070615-41; lrp2bp.
DR   eggNOG; KOG1550; Eukaryota.
DR   InParanoid; A5PLI4; -.
DR   OrthoDB; 5476873at2759; -.
DR   PhylomeDB; A5PLI4; -.
DR   PRO; PR:A5PLI4; -.
DR   Proteomes; UP000000437; Chromosome 14.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR006597; Sel1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR44554; LRP2-BINDING PROTEIN; 1.
DR   PANTHER; PTHR44554:SF1; LRP2-BINDING PROTEIN; 1.
DR   Pfam; PF08238; Sel1; 5.
DR   SMART; SM00671; SEL1; 5.
DR   SUPFAM; SSF81901; HCP-like; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..343
FT                   /note="LRP2-binding protein"
FT                   /id="PRO_0000315711"
FT   REPEAT          58..91
FT                   /note="TPR"
FT   REPEAT          92..124
FT                   /note="Sel1-like 1"
FT   REPEAT          132..167
FT                   /note="Sel1-like 2"
FT   REPEAT          172..205
FT                   /note="Sel1-like 3"
FT   REPEAT          206..241
FT                   /note="Sel1-like 4"
FT   REPEAT          242..273
FT                   /note="Sel1-like 5"
FT   REPEAT          293..328
FT                   /note="Sel1-like 6"
SQ   SEQUENCE   343 AA;  38144 MW;  65E8C9C6CB91B743 CRC64;
     MDCSELDSTE KSKPSQLLRA INQIYEEGRE ESTHSETNAA SVEKTMNLLK EKAETGDSQA
     TFLLGQLHYV QGCYAEAELI FDRIKDKDPQ ALYQLAVIYY DGLGTKEDLG RAVEYMGRVA
     FWDSSEAGSV RYAALYNLGQ AYLEGFGVQA SSSEAERLWL LAADNGNPNA SVKAQSALGM
     FYSRPESLDL RKAFFWHSQA CGNGSLESQA ALGLMYLYGH GVQRDSDSAL FCLKEAAERG
     SVYAQGHLTA CYYRRQLYSR AAALGQRVCE YKDTAAIAQQ TDCLEEYVRK GIAIGMFYYA
     RCLHLGRGVP QNRDKAKHYC TQAVRIDPLI CKELQIDAAH GKI
//