ID A5UZB3_ROSS1 Unreviewed; 577 AA.
AC A5UZB3;
DT 10-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 10-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=RoseRS_3611 {ECO:0000313|EMBL:ABQ91966.1};
OS Roseiflexus sp. (strain RS-1).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Roseiflexineae;
OC Roseiflexaceae; Roseiflexus.
OX NCBI_TaxID=357808 {ECO:0000313|EMBL:ABQ91966.1, ECO:0000313|Proteomes:UP000006554};
RN [1] {ECO:0000313|Proteomes:UP000006554}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS-1 {ECO:0000313|Proteomes:UP000006554};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.;
RT "Complete sequence of Roseiflexus sp. RS-1.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP000686; ABQ91966.1; -; Genomic_DNA.
DR RefSeq; WP_011958308.1; NC_009523.1.
DR AlphaFoldDB; A5UZB3; -.
DR STRING; 357808.RoseRS_3611; -.
DR KEGG; rrs:RoseRS_3611; -.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG3850; Bacteria.
DR HOGENOM; CLU_000445_89_2_0; -.
DR OrthoDB; 9790669at2; -.
DR Proteomes; UP000006554; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR024478; HlyB_4HB_MCP.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF12729; 4HB_MCP_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABQ91966.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABQ91966.1}.
FT DOMAIN 210..262
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 315..537
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 71..98
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 254..308
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 577 AA; 64409 MW; 34326F37D2B2FC28 CRC64;
MKLSIRTKLL AALGVDLLLM LVLGSFALHQ MSTMNQKADF VVNQTILSID LVNAMNDIIL
NYRTRQMEYI LNAAPADKQR IEKELLDLEQ RMDDMFRRYN ASYQPDQTER AVFEQVQKDW
ERYVHLTHTQ FIPANRNSNT GNVHPSFGRL SPLYGSLQTN IQKVREQSQA RAEAARVSVE
TAYATSRFVI VSETFLTLVV SAVIGLTLSG NIARRIRTLR DATVAVAQGD LDQRVALRGS
DELVLLANNF NLMVASLRQQ RVLLEERNAE LSASLEAQRK LMDDLVQRKQ AEEAAHRAQA
AAEAASHAKS MFLATMSHEL RTPLNAILGY VQLLHLEAHM RGRSEMLPDL ERIRSAGKHL
LTIISNILDF SKIEQGKMNV EINPFSVDTV AREVIGIIDP LARNRKNTLN LVCPPDAGMM
QSDAGKVRQI LFNLLSNAVK FTEEGTVTLT VERERHPDGD WVQFSVADTG IGIAPEQMAH
LFQPFYQVHQ NRSRNYGGTG LGLALSRQLC RLLGGDIRVT SEVGRGSVFT VRLPACIDAA
HTADVRLDFA HSAHYGIPDE YRITTTSSLH TTTSISA
//
