ID A5Z8F1_9FIRM Unreviewed; 586 AA.
AC A5Z8F1;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE SubName: Full=Nitrogen regulatory protein P-II {ECO:0000313|EMBL:EDM50674.1};
GN ORFNames=EUBVEN_01992 {ECO:0000313|EMBL:EDM50674.1};
OS Eubacterium ventriosum ATCC 27560.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=411463 {ECO:0000313|EMBL:EDM50674.1, ECO:0000313|Proteomes:UP000006000};
RN [1] {ECO:0000313|EMBL:EDM50674.1, ECO:0000313|Proteomes:UP000006000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27560 {ECO:0000313|EMBL:EDM50674.1,
RC ECO:0000313|Proteomes:UP000006000};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDM50674.1, ECO:0000313|Proteomes:UP000006000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27560 {ECO:0000313|EMBL:EDM50674.1,
RC ECO:0000313|Proteomes:UP000006000};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Eubacterium ventriosum (ATCC 27560).";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the P(II) protein family.
CC {ECO:0000256|RuleBase:RU003936}.
CC -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC family. {ECO:0000256|ARBA:ARBA00005887}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDM50674.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAVL02000036; EDM50674.1; -; Genomic_DNA.
DR AlphaFoldDB; A5Z8F1; -.
DR STRING; 411463.EUBVEN_01992; -.
DR eggNOG; COG0004; Bacteria.
DR HOGENOM; CLU_000445_33_1_9; -.
DR Proteomes; UP000006000; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030234; F:enzyme regulator activity; IEA:InterPro.
DR GO; GO:0006808; P:regulation of nitrogen utilization; IEA:InterPro.
DR Gene3D; 3.30.70.120; -; 1.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR001905; Ammonium_transpt.
DR InterPro; IPR018047; Ammonium_transpt_CS.
DR InterPro; IPR002187; N-reg_PII.
DR InterPro; IPR011322; N-reg_PII-like_a/b.
DR InterPro; IPR015867; N-reg_PII/ATP_PRibTrfase_C.
DR InterPro; IPR017918; N-reg_PII_CS.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR NCBIfam; TIGR00836; amt; 1.
DR PANTHER; PTHR11730; AMMONIUM TRANSPORTER; 1.
DR PANTHER; PTHR11730:SF89; AMMONIUM TRANSPORTER SLL0108-RELATED; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR Pfam; PF00543; P-II; 1.
DR PRINTS; PR00340; PIIGLNB.
DR SMART; SM00938; P-II; 1.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
DR SUPFAM; SSF54913; GlnB-like; 1.
DR PROSITE; PS01219; AMMONIUM_TRANSP; 1.
DR PROSITE; PS00638; PII_GLNB_CTER; 1.
DR PROSITE; PS51343; PII_GLNB_DOM; 1.
PE 3: Inferred from homology;
KW Ammonia transport {ECO:0000256|ARBA:ARBA00023177};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..426
FT /note="Ammonium transporter AmtB-like"
FT /evidence="ECO:0000259|Pfam:PF00909"
SQ SEQUENCE 586 AA; 62171 MW; 4871B845AE0D06F4 CRC64;
MEEGTMNAQE ILQEATNSSF AIWFLIGAGL VFFMQAGFAM VETGFTRAKN AGNIIMKNLM
DFCIGTLMYI ILGFGLMMSE DYVMGIIGVP NLDIFTNYNS FNWSQFVFQL VFCATAATIV
SGAMAERTKF SAYCIYSGAI SLIVYPIEAG WVWNLGGNGW LQQLHFVDFA GSAVIHSVGG
MAALVGAIIV GPRIGKYTKR SNGSIRSNAI AGHSITLGAL GCFILWFGWY GFNGAAATNV
DSLASIFMNT TIAPATATVV CMLFTWIKDG KPDVGMCLNA SLAGLVGITA GCASVDTIGA
LIIGAVSGIL VDVVVEVLDK KFHIDDPVGA VGVHWANGVW GTIAVGLFAT GRGDTVQAFA
DGSTYAGLFY GGGAKLLGIQ ILGIVAIDVY AAVMMTIVFQ LIKHTIGLRT TAEEEIIGMD
ISEHGLASAY ADFLPAAPSY AGESEGSVDL SDVKPVALTL GERAEGRYTK VSIICPEERF
GVLRDTMNAI GVMGMTVSQV MGCGAEKGKT GRYRGVSTTM NLYRKVQVDI VVSTVDPGLV
VAAARKALNT EHYGDGKIFV TNVEDVMRVR TGEVGVEALA YKNERK
//
