ID A5ZAQ6_9FIRM Unreviewed; 567 AA.
AC A5ZAQ6;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Penicillin-binding protein, transpeptidase domain protein {ECO:0000313|EMBL:EDM50157.1};
GN ORFNames=EUBVEN_02808 {ECO:0000313|EMBL:EDM50157.1};
OS Eubacterium ventriosum ATCC 27560.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=411463 {ECO:0000313|EMBL:EDM50157.1, ECO:0000313|Proteomes:UP000006000};
RN [1] {ECO:0000313|EMBL:EDM50157.1, ECO:0000313|Proteomes:UP000006000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27560 {ECO:0000313|EMBL:EDM50157.1,
RC ECO:0000313|Proteomes:UP000006000};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDM50157.1, ECO:0000313|Proteomes:UP000006000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27560 {ECO:0000313|EMBL:EDM50157.1,
RC ECO:0000313|Proteomes:UP000006000};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Eubacterium ventriosum (ATCC 27560).";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDM50157.1}.
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DR EMBL; AAVL02000038; EDM50157.1; -; Genomic_DNA.
DR RefSeq; WP_005360758.1; NZ_DS264270.1.
DR AlphaFoldDB; A5ZAQ6; -.
DR STRING; 411463.EUBVEN_02808; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_0_9; -.
DR OrthoDB; 9804124at2; -.
DR Proteomes; UP000006000; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..188
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 234..552
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 567 AA; 62940 MW; F235524C48C56FE7 CRC64;
MLMIYMAFII SICIIVIGKL IYLMVYKSEY YGAKALEIQE RERKIKAPRG EILDRNGKVI
ASNKTVCTIS VIYNQVKETE KVIEILAKEL EMTDKEVRKK VTKRSSREKI KSNVPKEKGD
AIRNYNLSGV KVDEDYKRYY PYSSLASKVL GFTGADNQGI IGLEIKYDKY LKGTDGLILT
PTDSRGVEQE KALEQRVEPV SGNSLTTSID VNIQKYSEQI AYNALKAKQA NYVSIIVMNP
NNGEILAMVN VPEFDLNNPY KLIYETDNNI SAKEKQKLLN KMWRNQCIND TYEPGSTFKV
VTATAALEEG AVTIDSKFNC PGFKIVEDRK IRCHKITGHG SEDFLHGTMN SCNPVFIEVG
LKVGAKNFYK YLGKLGLLNR TGIDIPGEAS TIIHKIQNVG EVELATMSFG QSFQITPMQY
LVAASAVVNG GTLVTPHFAV KAENADNKLV EKFQYKSQSN VISKNTSETM KFILEKVVSE
GTGSKGQVPG FKVGGKTATS QKLPRGSGRY IASYMSFAPA DKPKVIAMAI IDEPKGIYYG
GQVAAPLISQ LYKNILPYLL EGEKQGE
//
