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Database: UniProt
Entry: A6CF48_9PLAN
LinkDB: A6CF48_9PLAN
Original site: A6CF48_9PLAN 
ID   A6CF48_9PLAN            Unreviewed;       414 AA.
AC   A6CF48;
DT   24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2007, sequence version 1.
DT   28-MAR-2018, entry version 62.
DE   RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 2 {ECO:0000256|PIRNR:PIRNR000447};
DE            EC=2.3.1.179 {ECO:0000256|PIRNR:PIRNR000447};
GN   ORFNames=PM8797T_17784 {ECO:0000313|EMBL:EDL56714.1};
OS   Gimesia maris DSM 8797.
OC   Bacteria; Planctomycetes; Planctomycetia; Planctomycetales;
OC   Planctomycetaceae; Gimesia.
OX   NCBI_TaxID=344747 {ECO:0000313|EMBL:EDL56714.1, ECO:0000313|Proteomes:UP000003087};
RN   [1] {ECO:0000313|EMBL:EDL56714.1, ECO:0000313|Proteomes:UP000003087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 8797T {ECO:0000313|Proteomes:UP000003087};
RA   Amann R., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the condensation reaction of fatty acid
CC       synthesis by the addition to an acyl acceptor of two carbons from
CC       malonyl-ACP. {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- CATALYTIC ACTIVITY: (Z)-hexadec-11-enoyl-[acyl-carrier-protein] +
CC       malonyl-[acyl-carrier-protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-
CC       carrier-protein] + CO(2) + [acyl-carrier-protein].
CC       {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC       {ECO:0000256|PIRNR:PIRNR000447}.
CC   -!- SIMILARITY: Belongs to the beta-ketoacyl-ACP synthases family.
CC       {ECO:0000256|PIRNR:PIRNR000447, ECO:0000256|RuleBase:RU003694}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EDL56714.1}.
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DR   EMBL; ABCE01000052; EDL56714.1; -; Genomic_DNA.
DR   RefSeq; WP_002649180.1; NZ_ABCE01000052.1.
DR   ProteinModelPortal; A6CF48; -.
DR   STRING; 344747.PM8797T_17784; -.
DR   EnsemblBacteria; EDL56714; EDL56714; PM8797T_17784.
DR   eggNOG; ENOG4105C0Q; Bacteria.
DR   eggNOG; COG0304; LUCA.
DR   OrthoDB; POG091H018O; -.
DR   UniPathway; UPA00094; -.
DR   Proteomes; UP000003087; Unassembled WGS sequence.
DR   GO; GO:0033817; F:beta-ketoacyl-acyl-carrier-protein synthase II activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR017568; 3-oxoacyl-ACP_synth-2.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   PIRSF; PIRSF000447; KAS_II; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR03150; fabF; 1.
DR   PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|PIRNR:PIRNR000447};
KW   Complete proteome {ECO:0000313|Proteomes:UP000003087};
KW   Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000447};
KW   Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000447};
KW   Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000447};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000447};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003087};
KW   Transferase {ECO:0000256|PIRNR:PIRNR000447,
KW   ECO:0000256|RuleBase:RU003694}.
FT   DOMAIN        5    414       PKS_KS. {ECO:0000259|SMART:SM00825}.
FT   ACT_SITE    165    165       {ECO:0000256|PIRSR:PIRSR000447-1}.
SQ   SEQUENCE   414 AA;  44376 MW;  48032603A837603C CRC64;
     MRRRVVVTGV SVVTALGLDV SEFWDKLCAG KSGIGPLERF DCSDYKVRFG GEIKDFNASE
     YTNISAKDLK RVDRFVQFAL VGAHIAYRQA QLEEFEGDPY RRGVLVGSGI GGLNEIESQH
     DRLYNQGPAR VSPFMIPKLM VNAASGNISV TYELKGPNSA VATACASATN AIGDAFKLIQ
     HDVADIMITG GSEAAVTPMG LSGFARMNAL STRNDDPQSA SRPFDRDRDG FVMAEGAGII
     VLEEYEHAKK RGVPILAEVI GYGMSADGTH MTAPDPEGRG AARAMLHAIK DAGVNPEDID
     YINTHGTSTP LGDVAETAAI NTVFNSHVKQ MPVSSTKGHL GHLLGASGGV EFVVGVKALQ
     EQVAPPTINL DNPDEQCNLD YIPNEPREMK LNRVMKNSFG FGGHNACLIL QKAP
//
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