ID   A6EBU0_9SPHI            Unreviewed;       357 AA.
AC   A6EBU0;
DT   24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2007, sequence version 1.
DT   22-FEB-2023, entry version 41.
DE   SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:EDM37189.1};
GN   ORFNames=PBAL39_05303 {ECO:0000313|EMBL:EDM37189.1};
OS   Pedobacter sp. BAL39.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=391596 {ECO:0000313|EMBL:EDM37189.1, ECO:0000313|Proteomes:UP000003664};
RN   [1] {ECO:0000313|EMBL:EDM37189.1, ECO:0000313|Proteomes:UP000003664}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BAL39 {ECO:0000313|EMBL:EDM37189.1,
RC   ECO:0000313|Proteomes:UP000003664};
RA   Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDM37189.1}.
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DR   EMBL; ABCM01000005; EDM37189.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6EBU0; -.
DR   STRING; 391596.PBAL39_05303; -.
DR   eggNOG; COG2089; Bacteria.
DR   Proteomes; UP000003664; Unassembled WGS sequence.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   InterPro; IPR013974; SAF.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF2; PSEUDAMINIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   Pfam; PF08666; SAF; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000003664}.
FT   DOMAIN          300..357
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   357 AA;  39744 MW;  F59AE1CB820C1F04 CRC64;
     MNNMNTIKFG TRTIGQGHPL YFVADIGANH DGDLQKALDL IEMAKEAGAD AAKFQHFQAS
     KIVSRVGFDS LGGQLSHQAS WKKSVYEVYE DASINQDWTP ILKKRCDEIG IDFFTSPYDF
     KSVDDVDQYV DLYKVGSGDI TWIEIIKYIA NKNKPVLIAT GASDMPDVER AMNAIQPLTK
     DIVLMQCNTN YTVEKDKHKY SNLNVLKTFS TKYPDTILGL SDHTFSHSTV LGAVALGALV
     FEKHFTNSND QDGPDHKFAV NPAAWREMVD RANELYEALG DGIKRVEENE LQSAIVQRRS
     LRLTSDLPAG HTLSAGDLEP LRPITSDGLE PYKIDEVIGH VLKENLKQGA EITLNHI
//