ID A6M0C8_CLOB8 Unreviewed; 271 AA.
AC A6M0C8;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Nitroreductase {ECO:0000313|EMBL:ABR36058.1};
GN OrderedLocusNames=Cbei_3948 {ECO:0000313|EMBL:ABR36058.1};
OS Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium
OS acetobutylicum).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=290402 {ECO:0000313|EMBL:ABR36058.1, ECO:0000313|Proteomes:UP000000565};
RN [1] {ECO:0000313|EMBL:ABR36058.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G.,
RA Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W.,
RA Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B.,
RA Blaschek H., Richardson P.;
RT "Complete sequence of Clostridium beijerinckii NCIMB 8052.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABR36058.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RX PubMed=21962126; DOI=10.1186/1471-2164-12-479;
RA Wang Y., Li X., Mao Y., Blaschek H.P.;
RT "Single-nucleotide resolution analysis of the transcriptome structure of
RT Clostridium beijerinckii NCIMB 8052 using RNA-Seq.";
RL BMC Genomics 12:479-479(2011).
RN [3] {ECO:0000313|EMBL:ABR36058.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RX PubMed=22433311; DOI=10.1186/1471-2164-13-102;
RA Wang Y., Li X., Mao Y., Blaschek H.P.;
RT "Genome-wide dynamic transcriptional profiling in clostridium beijerinckii
RT NCIMB 8052 using single-nucleotide resolution RNA-Seq.";
RL BMC Genomics 13:102-102(2012).
CC -!- SIMILARITY: Belongs to the nitroreductase family.
CC {ECO:0000256|ARBA:ARBA00007118}.
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DR EMBL; CP000721; ABR36058.1; -; Genomic_DNA.
DR RefSeq; WP_012060106.1; NC_009617.1.
DR AlphaFoldDB; A6M0C8; -.
DR KEGG; cbe:Cbei_3948; -.
DR eggNOG; COG0778; Bacteria.
DR eggNOG; COG1145; Bacteria.
DR HOGENOM; CLU_070764_2_0_9; -.
DR Proteomes; UP000000565; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02143; nitroreductase_FeS-like; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR PANTHER; PTHR43673; NAD(P)H NITROREDUCTASE YDGI-RELATED; 1.
DR PANTHER; PTHR43673:SF2; NITROREDUCTASE FAMILY PROTEIN; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 2..31
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 32..61
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 271 AA; 30212 MW; 7F0069666464AF83 CRC64;
MELITVNQST CVKCGLCSNV CPSGVLSMNE NGPIAIHPDN CISCGHCVAI CPSSSIDNIK
TPLSNQLDLE SFPLIDSSTA ESFLRSRRSI RCYKETQVPQ QTLLKLVNIA RFAPTASNTQ
GLSYIIIKNK KILQQAANIV VEWMEDQLKN SPSPHWSFSR HVKNYRDAGE DSILRNTPHI
ILATSTKDFK NGIKNTISAF SYLELFATTL GLGSCWAGLF EMCAFSNYKP LLELLRIPDN
KVITGAVMVG YPKYKYRKIV DRNPLEVEFI N
//
