ID A6M2A7_CLOB8 Unreviewed; 620 AA.
AC A6M2A7;
DT 24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Polysaccharide biosynthesis protein CapD {ECO:0000313|EMBL:ABR36737.1};
GN OrderedLocusNames=Cbei_4629 {ECO:0000313|EMBL:ABR36737.1};
OS Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium
OS acetobutylicum).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=290402 {ECO:0000313|EMBL:ABR36737.1, ECO:0000313|Proteomes:UP000000565};
RN [1] {ECO:0000313|EMBL:ABR36737.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G.,
RA Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W.,
RA Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B.,
RA Blaschek H., Richardson P.;
RT "Complete sequence of Clostridium beijerinckii NCIMB 8052.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABR36737.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RX PubMed=21962126; DOI=10.1186/1471-2164-12-479;
RA Wang Y., Li X., Mao Y., Blaschek H.P.;
RT "Single-nucleotide resolution analysis of the transcriptome structure of
RT Clostridium beijerinckii NCIMB 8052 using RNA-Seq.";
RL BMC Genomics 12:479-479(2011).
RN [3] {ECO:0000313|EMBL:ABR36737.1, ECO:0000313|Proteomes:UP000000565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51743 / NCIMB 8052 {ECO:0000313|Proteomes:UP000000565};
RX PubMed=22433311; DOI=10.1186/1471-2164-13-102;
RA Wang Y., Li X., Mao Y., Blaschek H.P.;
RT "Genome-wide dynamic transcriptional profiling in clostridium beijerinckii
RT NCIMB 8052 using single-nucleotide resolution RNA-Seq.";
RL BMC Genomics 13:102-102(2012).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; CP000721; ABR36737.1; -; Genomic_DNA.
DR RefSeq; WP_012060784.1; NC_009617.1.
DR AlphaFoldDB; A6M2A7; -.
DR KEGG; cbe:Cbei_4629; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_5_2_9; -.
DR Proteomes; UP000000565; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 282..564
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 620 AA; 69915 MW; 4078A61EAE6825EE CRC64;
MKNWKTFIVM IIDMFMVNMA YLFSINITNS GDFTLIAKIY THDCIALSLI YLVCFYLFKM
YESLWHLTGT DEFLLGVGGN ILAGIISIGY TRILGNTIPL NVSVVGILLS IFFVLGYRIL
YRVYRRTLLY IPFKYSSDQR RVMIVGAGSA GTMLINEMMA RRELKYNPIV LIDDDKSKLG
KRISGVKIEG NRYDIPYIVG DQEIDLILIA IPSLDAKNKA EIIEICKNTN CKLQIIPGMY
EILSGDATVS RIKDVDLEDL LGRDPIQLDN KGISDYIEGK TILVTGGGGS IGSELCRQIS
VYNPKRLIIF DIYENNVYDI QNELREEFPD MNLTVLIGSV RDKKRLHEIF TKYRVNVVFH
AAAHKHVPLM EDSPKEAIKN NVFGTLNLAL EASEANVERF VMISTDKAVN PTNIMGATKR
LCEMIIQAMD KQSRTEFVAV RFGNVLGSNG SVIPLFKRQI ANGGPVTVTH KKIIRYFMLI
PEAAQLVLQA GAFARGGEVF VLDMGKPVKI YDLACDLIRL SGLEPNRDIK IVVTGLRPGE
KLYEELLMSE EGLENTVHNK IYVGKPTFED MNSLTIKLEQ LQKLLELSDI SEIKHQMQKI
VPTYHYKNED EVAAENADKE
//
