ID A6Q7H4_SULNB Unreviewed; 1030 AA.
AC A6Q7H4;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Cation/multidrug efflux transporter, RND superfamily {ECO:0000313|EMBL:BAF71433.1};
GN OrderedLocusNames=SUN_0473 {ECO:0000313|EMBL:BAF71433.1};
OS Sulfurovum sp. (strain NBC37-1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Sulfurovaceae; Sulfurovum.
OX NCBI_TaxID=387093 {ECO:0000313|EMBL:BAF71433.1, ECO:0000313|Proteomes:UP000006378};
RN [1] {ECO:0000313|EMBL:BAF71433.1, ECO:0000313|Proteomes:UP000006378}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBC37-1 {ECO:0000313|EMBL:BAF71433.1,
RC ECO:0000313|Proteomes:UP000006378};
RX PubMed=17615243; DOI=10.1073/pnas.0700687104;
RA Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K.,
RA Horikoshi K.;
RT "Deep-sea vent epsilon-proteobacterial genomes provide insights into
RT emergence of pathogens.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007).
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DR EMBL; AP009179; BAF71433.1; -; Genomic_DNA.
DR RefSeq; WP_011980166.1; NC_009663.1.
DR AlphaFoldDB; A6Q7H4; -.
DR STRING; 387093.SUN_0473; -.
DR KEGG; sun:SUN_0473; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_7; -.
DR OrthoDB; 8430015at2; -.
DR Proteomes; UP000006378; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF33; RND SUPERFAMILY EFFLUX PUMP PERMEASE COMPONENT; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 512..533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 873..892
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 899..919
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 925..947
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 968..986
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 998..1023
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1030 AA; 115534 MW; 13429EDD1FB7A083 CRC64;
MFEKLLRFFV ENSRLNYFLF ILIFLTGAVL YTKTPKEIFP SFELDMVSVN GHYAGASIDM
LNKMAVKEIE QELKNIDGID KMATIISAGK FNIILELEKR VDKYNTAEKV KNAIALTKQY
LPSDMDEPVV NVLEVKRDLM RVAISSQKAP HSALIEAADR LKDKVSALKN ISEVKIFGDS
DKYYDIHLDT QKIRAYGLDE STVVAALTGL SYIFPVGMIE ESDAKHFYLS TYNGPKDAQK
MLQSQLDIGG KTLYLKDIAT VSKRYEDAAT IYSIDGKNAV DVSIKQSSEG NALKLAEQIR
EIVARMNQNS KGIYFTIHND RSEKIKDRLN IVISNILLGL ILISLLVGIL INWRMSLVIT
LGIPTSFVMG VIYLYLAGYT INMISLVGVL IALGIIVDDA IVVSENIQQH IEEGLEPKEA
AIQGAKEMFK PVTIASLTTL FAFIPALMMS GNMGEVIKLI PIAVSVLVLA SLIESFLFLP
IHAAHLLNKN EKTTSWERAN RIYSKLIHKL MYYRKTFLTL FLILVPLLIV IGVKSSKFQM
FPKFDASTIR ITLKANVNTS TEETMRALKA IEKDLYAHKD EFYIEHIGSV AGWRRDSAGN
SESYPYVGNI DIELQKLKAQ NLVDRFITPT LSFYYDSEGR TRKEKSAVIS EKLRAFLKQQ
HYKKRFGLSD LAIVERKVGP IKSDLKIGLV SDDSQKIMKY AKKIEEKLSS LKGIVSVNDA
MHYGVDEIKL KVNSYGESLG LNEKKLGALL SNFYLEKRIG FAFDSSDLLE LKVRSSQKDS
LEALKQFQIR LDNGSSVSLE DVADFHIIRS FEKVIKDNGL TNFYIYANVN SKVLTATEAI
DAIKPILEKA KKEGIKIIFK GEEEKKKELK HDMMLASAMA MLLIMLSLLY LFNSFRETFM
IMTVIPFAFL GVLIGHFVMG LNLSMPSIIG MLGLSGVVIN DGIIMLMNLK RAKDLEGIYY
YASKRFRPII LTSVTTLIGL ASLVFFPTGQ AAIFQPMAIS LAFGLAWGTV LNLLYLPALY
TILNQKKLGM
//
