ID A6QPR4_BOVIN Unreviewed; 338 AA.
AC A6QPR4;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=APOL3 protein {ECO:0000313|EMBL:AAI49446.1};
DE SubName: Full=Apolipoprotein L, 3 {ECO:0000313|Ensembl:ENSBTAP00000000878.5};
GN Name=APOL3 {ECO:0000313|EMBL:AAI49446.1,
GN ECO:0000313|Ensembl:ENSBTAP00000000878.5};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI49446.1};
RN [1] {ECO:0000313|EMBL:AAI49446.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hereford {ECO:0000313|EMBL:AAI49446.1};
RC TISSUE=Placenta {ECO:0000313|EMBL:AAI49446.1};
RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., Siddiqui A.,
RA Holt R., Jones S.J., Marra M.A.;
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000000878.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000000878.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSBTAP00000000878.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000000878.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the apolipoprotein L family.
CC {ECO:0000256|ARBA:ARBA00010090}.
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DR EMBL; BC149445; AAI49446.1; -; mRNA.
DR RefSeq; NP_001093821.1; NM_001100351.1.
DR RefSeq; XP_005206876.1; XM_005206819.3.
DR RefSeq; XP_005206880.1; XM_005206823.3.
DR RefSeq; XP_005206881.1; XM_005206824.3.
DR RefSeq; XP_010803636.1; XM_010805334.2.
DR RefSeq; XP_010803637.1; XM_010805335.2.
DR RefSeq; XP_015326658.1; XM_015471172.1.
DR STRING; 9913.ENSBTAP00000000878; -.
DR PaxDb; 9913-ENSBTAP00000000878; -.
DR Ensembl; ENSBTAT00000000878.6; ENSBTAP00000000878.5; ENSBTAG00000000667.6.
DR GeneID; 512905; -.
DR KEGG; bta:512905; -.
DR VEuPathDB; HostDB:ENSBTAG00000000667; -.
DR eggNOG; ENOG502RZGU; Eukaryota.
DR GeneTree; ENSGT01030000234599; -.
DR HOGENOM; CLU_046288_1_0_1; -.
DR OMA; WRTKVAQ; -.
DR OrthoDB; 5323587at2759; -.
DR TreeFam; TF334681; -.
DR Reactome; R-BTA-381426; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs).
DR Reactome; R-BTA-8957275; Post-translational protein phosphorylation.
DR Proteomes; UP000009136; Chromosome 5.
DR Bgee; ENSBTAG00000000667; Expressed in duodenum and 89 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IBA:GO_Central.
DR GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR InterPro; IPR008405; ApoL.
DR PANTHER; PTHR14096; APOLIPOPROTEIN L; 1.
DR PANTHER; PTHR14096:SF27; APOLIPOPROTEIN L2; 1.
DR Pfam; PF05461; ApoL; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 338 AA; 36878 MW; 66D1D90A70A07C7C CRC64;
MSSEDRRKSS ESENFFEDII QYLKDSVSRE QLELLLTEKE AWETFVAEAD LSREEANVLY
EYLLELKTDL VEEDQDRPQQ DQLDRKRFLE EFPRVKQELE ETIAKLHALA DKVDKVHRDC
TVTNVVASSA GAVSGVLTIL GLALAPMTAG ISLGLSATGL GLGAAAAVTS VSTSIVEHVS
RSSAETEASR LGPIAINEGE VFAEVLCKRT PQIVSSTKNL IQALKGIGKN VRAIKLAKVN
PRLASHAKRF MTVGQVSARS SKQVQRAFGG TALAMTKSAR IVGAATAGAA LLVDVAFLVK
EAKHLHEGAK TESAERMRQM AKELEKKLEE LIRTYESL
//
