ID A6QTR8_AJECN Unreviewed; 370 AA.
AC A6QTR8;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=RNase III domain-containing protein {ECO:0000259|PROSITE:PS50142};
GN ORFNames=HCAG_00774 {ECO:0000313|EMBL:EDN02910.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN02910.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476655; EDN02910.1; -; Genomic_DNA.
DR AlphaFoldDB; A6QTR8; -.
DR STRING; 339724.A6QTR8; -.
DR VEuPathDB; FungiDB:HCAG_00774; -.
DR HOGENOM; CLU_034765_3_0_1; -.
DR OMA; YLYSPGN; -.
DR OrthoDB; 1384985at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 1.10.1520.10; Ribonuclease III domain; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR PANTHER; PTHR11207:SF32; 54S RIBOSOMAL PROTEIN L3, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11207; RIBONUCLEASE III; 1.
DR Pfam; PF00035; dsrm; 1.
DR SMART; SM00535; RIBOc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF69065; RNase III domain-like; 1.
DR PROSITE; PS50142; RNASE_3_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 61..241
FT /note="RNase III"
FT /evidence="ECO:0000259|PROSITE:PS50142"
SQ SEQUENCE 370 AA; 40691 MW; 23C3E75B9A98ED5C CRC64;
MVSAPHQFYF TAIRQQSSAS SSVLAEENEL CDDEHSSGFH VNRTPTPPSP PVEAALNSPK
LSAIHSRLSL PQRLPLQTLA RTLVDESADP SPQFNNKSLS ILGSDLLTYY TAEHLISTYP
RLPVKVLWAA MYSYIGAKPL AAMTREWGLE YAAEPGPEVD PGLLQFKRLP PDTGFETKSN
GTFLRRDENM AKRSTSARII YGGAFGESTL PYPVHHEGVT PNRACANFIR AVVGAVYLHA
GRPAAKQFFK EHFMSRHLDM ASLFSFRQPT RDLSKLCRRE GFEDPVAKIL SETGRHSNRP
VFNVGIFSGP DKLGEGAGGS LSEARFRAAA AALKGWYLYS PLGVRVPSSM EEEGAEPWKP
VYVDPGEVIV
//
