ID A6QWI0_AJECN Unreviewed; 1060 AA.
AC A6QWI0;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=CCAAT-binding factor domain-containing protein {ECO:0000259|Pfam:PF03914};
GN ORFNames=HCAG_01737 {ECO:0000313|EMBL:EDN03872.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN03872.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SIMILARITY: Belongs to the CBF/MAK21 family.
CC {ECO:0000256|ARBA:ARBA00007797}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH476655; EDN03872.1; -; Genomic_DNA.
DR AlphaFoldDB; A6QWI0; -.
DR STRING; 339724.A6QWI0; -.
DR VEuPathDB; FungiDB:HCAG_01737; -.
DR HOGENOM; CLU_003417_0_0_1; -.
DR OMA; EIWCNDE; -.
DR OrthoDB; 1214522at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR005612; CCAAT-binding_factor.
DR InterPro; IPR040155; CEBPZ/Mak21-like.
DR PANTHER; PTHR12048; CCAAT-BINDING FACTOR-RELATED; 1.
DR PANTHER; PTHR12048:SF0; CCAAT_ENHANCER-BINDING PROTEIN ZETA; 1.
DR Pfam; PF03914; CBF; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 593..767
FT /note="CCAAT-binding factor"
FT /evidence="ECO:0000259|Pfam:PF03914"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 52..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 163..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..892
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 990..1033
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..178
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..744
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 922..963
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1060 AA; 118780 MW; AFF384B33EE9B8A3 CRC64;
MGKPKTKERR SSANGVPNTA SEMPANPLTL NADSLPDLSL SVLAKLKRRI EQGFQDQEPQ
SQKDKKVSLS ELKQKTNAGP QSEPKAVNKK GKKRDRNGEI IAPQEGKEKP RSKFDERGEN
GNLLENEIYA IGGTKEDYDL LADVESDSEM EIFEDTPRKY SAKAVNEHTL RNDIEKMLKG
DNPSPPPKPA SKKAVVADIV PIDPKPAKES KSLQQVKPSK EAPKQNTLKK PNPNQEEVSV
PGRLAQQRDT RSSNLAIDPR PDWYSIPLPE VSLESKKCSG ISRQIWDRIR EYAASLLDSE
NQAFATSQQS SSSHKFYSTI VSSGTLSDKV SALTLAVQES PLHNVRALEN LIGLAKKRSR
AQAIEVLRSL KDIFAQGTLL PSDRRLKSLI NQPALVSAFD GVSSNWTSSN PLPKGLERSH
LIVWAFEDFL KEQYFEVLKI LEIWCNDEIE FSRSKALSNP NILFRPGQSQ HAKYYAIITL
NQTILRSGEE NVATKLLDIY FALFVTLLKP TKSSTSNSER KHGKHDAKSK KRHGGAAIPK
GQAQETELHE KLTAAVLTGV NRAYPFTSSD VEKLSRHIDT LFRITHSSNF NTSIQALVLI
QQLSSSHQVS LHRFYRTLYE SLLDPRLSTS SKQSMYLNIL YKSLKADFNV KRVKAFVKRL
VQTLSLHHPP FICGVFYLIR ELEKAFPNLS ALMDEPENIE DDDEEVFRDV PEDGEQPVDQ
TPVDEGKKVE NRYDPRKRDP EHSNADRSCL WELLPYLAHF HPSVSVNASH LLHHEPMSGK
PDLSIHTLTH FLDRFVYRNP KATPRMRGAS IMQPLAGGES KGLLITSGGM AKAHEPVNRE
EFWKKQSDEV AAEDVFFHEY FNRMDKDNLR KQKSKKKLGA REKGEDESDA ESEIWKALVH
SRPELEGEGE SEDGIDIDDF ASAMGDEEDD GLGDVEMGDM ESLDDDEEAE VIFNDESDEP
EVEVEQSGRD SAQDIDSFGG FMDEDALEMD VSDEDAFRGS DDDLPSDLDN GVEELLAETS
GKGNKSTSRQ KRKKLKHLPV FASVDDYAAL LADENPDDGI
//
