ID   A6R068_AJECN            Unreviewed;       377 AA.
AC   A6R068;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   RecName: Full=SMP-30/Gluconolactonase/LRE-like region domain-containing protein {ECO:0000259|Pfam:PF08450};
GN   ORFNames=HCAG_03025 {ECO:0000313|EMBL:EDN06422.1};
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN06422.1, ECO:0000313|Proteomes:UP000009297};
RN   [1] {ECO:0000313|Proteomes:UP000009297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
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DR   EMBL; CH476656; EDN06422.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6R068; -.
DR   STRING; 339724.A6R068; -.
DR   VEuPathDB; FungiDB:HCAG_03025; -.
DR   HOGENOM; CLU_036110_1_3_1; -.
DR   OMA; RVYAGCG; -.
DR   OrthoDB; 2246590at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR013658; SGL.
DR   PANTHER; PTHR47064; PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08990)-RELATED; 1.
DR   PANTHER; PTHR47064:SF2; SMP-30_GLUCONOLACTONASE_LRE-LIKE REGION DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF08450; SGL; 2.
DR   SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT   DOMAIN          129..248
FT                   /note="SMP-30/Gluconolactonase/LRE-like region"
FT                   /evidence="ECO:0000259|Pfam:PF08450"
FT   DOMAIN          259..346
FT                   /note="SMP-30/Gluconolactonase/LRE-like region"
FT                   /evidence="ECO:0000259|Pfam:PF08450"
SQ   SEQUENCE   377 AA;  41378 MW;  09EA71C93CAC4E65 CRC64;
     MHPPALASTT KIAYFDTKRA ATDSSYARSF SSAPSFVVYS DKFINDVLGL NARLSLVSSR
     KDAKDKFAHE AGVYIPSTNS IYFTSNYQTS DPRIDLYAIT ADTWQIEKLT EKPGFDIVSQ
     PNGACNYQGK ILYCAQGNMD TGGGNGKPSA LTLVDPVCGT ADTLINNFHG REFSSINDVV
     VHHGTRDIWF TDPTYGFEQA FRPVPELPKQ VYCFRPSTCQ CWVVADGFSM CNGLCFNPDY
     TLMYISDTGA IQSHGHIGDG HNFSFCGTSP ASIYVYDVVD GGTRLANRRL FAYCDNGVPD
     GIKCDEKGFV YSGCGDGVHV WDPKGHLVGK IVVGSTTANF CFGKEGLWMF AEEELWFYKP
     GFDILNLGGL RAGKLFL
//