ID A6R3Q9_AJECN Unreviewed; 559 AA.
AC A6R3Q9;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=PWI domain-containing protein {ECO:0000259|PROSITE:PS51025};
GN ORFNames=HCAG_04267 {ECO:0000313|EMBL:EDN07757.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN07757.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476658; EDN07757.1; -; Genomic_DNA.
DR AlphaFoldDB; A6R3Q9; -.
DR STRING; 339724.A6R3Q9; -.
DR VEuPathDB; FungiDB:HCAG_04267; -.
DR HOGENOM; CLU_032410_4_0_1; -.
DR OMA; DHEMKDP; -.
DR OrthoDB; 276172at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1390.10; PWI domain; 1.
DR InterPro; IPR002483; PWI_dom.
DR InterPro; IPR036483; PWI_dom_sf.
DR PANTHER; PTHR23148; SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN; 1.
DR PANTHER; PTHR23148:SF0; SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1; 1.
DR Pfam; PF01480; PWI; 1.
DR SMART; SM00311; PWI; 1.
DR SUPFAM; SSF101233; PWI domain; 1.
DR PROSITE; PS51025; PWI; 1.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 12..111
FT /note="PWI"
FT /evidence="ECO:0000259|PROSITE:PS51025"
FT REGION 148..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..247
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..286
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..376
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..413
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 65305 MW; 2274B4324F22D956 CRC64;
MATTAEAKLI RQTKFPPEFS KKVDMQKVNI EVMKKWIAGK ISGILGNEDD VVIELCFNLL
EGSRFPDIKL LQIQLTGFLD KDTPKFCKEL WNLCLSAQNN PQGVPKELLE AKKLELRQEK
LESERLAEEA RRRREEERMR ERELEALRQQ ERAERGRRSG RDRWADRDAR SPPSRRRSLD
RYRDHGRRKA DTWAPSGGRS SRWSDDRGRR TSRSISRSIS RSTSSSSLSP SPHRRARGRH
GPTRRRRSLS YSRSPDRRDR KRRRRRSPDR DDVLTRSTSV NRPDRSRSPR GRRRKSLTSS
SRSLSRTVSR HVSTSRSPPS LSSLRHRSRS RSPFRANGDK RGARARGRRS PSPAAKAYRT
NSRADITKDH PKSRDDRRRR SRSRSRSRSR SRNHNRSRER PSYRRRKNPS GSRSRTRSRS
PFRDRDRNRN RDRSRSGSRG TPRDRSDRKR HQSIERYAPA PRRRYKSPST WSSSAPEKRQ
TIVADSQEEE KEKKSSHSPP PASRSSKSSE AEPRRESQPE RKGLQDRVEE EDKEKEDGQA
AGVEVVQVNP ALQIPIDRY
//
