ID A6R9Q2_AJECN Unreviewed; 457 AA.
AC A6R9Q2;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=C3HC zinc finger domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HCAG_05690 {ECO:0000313|EMBL:EDN09887.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN09887.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CH476661; EDN09887.1; -; Genomic_DNA.
DR AlphaFoldDB; A6R9Q2; -.
DR STRING; 339724.A6R9Q2; -.
DR VEuPathDB; FungiDB:HCAG_05690; -.
DR HOGENOM; CLU_031412_0_0_1; -.
DR OMA; HLDYCPW; -.
DR OrthoDB; 1041481at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR InterPro; IPR013909; NIPA/Rsm1_C.
DR InterPro; IPR012935; Znf_C3HC-like.
DR PANTHER; PTHR15835; NUCLEAR-INTERACTING PARTNER OF ALK; 1.
DR PANTHER; PTHR15835:SF6; ZINC FINGER C3HC-TYPE PROTEIN 1; 1.
DR Pfam; PF08600; Rsm1; 1.
DR Pfam; PF07967; zf-C3HC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009297};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 112..180
FT /note="C3HC-type"
FT /evidence="ECO:0000259|Pfam:PF07967"
FT DOMAIN 291..383
FT /note="Nuclear-interacting partner of ALK/Rsm1-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08600"
FT REGION 38..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 50562 MW; 2FBB619B2A437B0A CRC64;
MNPPGSCTTA KLISSMSYAL ATKKRKFHRV LDSLSGANLQ RSSNASSSTT TPHATQTDSN
TPTLCPTIKR VRVASSGSVT NPDGMVARKS VSNTSLDSSQ QPSSQPRPNF VPWDRERFLE
RLETFRRVDR WSPKPASINE VQWAKRGWSC VDVMRVECVG GCGCAVVVKL PEDVDDVGED
EADKIIERRE VDTIQRLPLT NPETAVNSLH TRYLNLASLE SKLPPIDNIQ LPSELDLDET
LRILPPTFLS DTLECVTGQP TDKLPEQPID HDSSRTNISC QNGDGKVNKS AFALATFGWD
ATPDIGAGLA TCGACFRRLG LWMYKPKEDG SISVYAKLDV VGEHLDYCPW VNPETQSGGR
KPVLHGFDGK RQSGWEILAQ AIKTVHRRRT RGDIPSTPAE AAEASNQESL ANPAEDKLDD
DEKRKLRDRE WWIKLRRVRQ SLQAKSPKKT GYVAGGR
//
