ID A6RA04_AJECN Unreviewed; 340 AA.
AC A6RA04;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Alpha/beta hydrolase fold-3 domain-containing protein {ECO:0000259|Pfam:PF07859};
GN ORFNames=HCAG_05792 {ECO:0000313|EMBL:EDN09989.1};
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=2059318 {ECO:0000313|EMBL:EDN09989.1, ECO:0000313|Proteomes:UP000009297};
RN [1] {ECO:0000313|Proteomes:UP000009297}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
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DR EMBL; CH476661; EDN09989.1; -; Genomic_DNA.
DR AlphaFoldDB; A6RA04; -.
DR VEuPathDB; FungiDB:HCAG_05792; -.
DR HOGENOM; CLU_042179_0_0_1; -.
DR OMA; RETDWSV; -.
DR OrthoDB; 1366960at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013094; AB_hydrolase_3.
DR InterPro; IPR033140; Lipase_GDXG_put_SER_AS.
DR PANTHER; PTHR48081; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR PANTHER; PTHR48081:SF8; STERYL ACETYL HYDROLASE MUG81-RELATED; 1.
DR Pfam; PF07859; Abhydrolase_3; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS01174; LIPASE_GDXG_SER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009297}.
FT DOMAIN 84..285
FT /note="Alpha/beta hydrolase fold-3"
FT /evidence="ECO:0000259|Pfam:PF07859"
FT ACT_SITE 152
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10038"
SQ SEQUENCE 340 AA; 37457 MW; 62F03B6DB5A9228B CRC64;
MTSLYSTTQA NALTIREKAL YYALIPVFGS AIKSYCTRHR IPLKTILVNH TTPAKSKVDL
SVYAPPPTLH FATPPSATAD GPVLLYFHGG GYVNPLRAIA HIPFVLRCVF LEYALAPEHR
YPVQLVQAVS ALRYLLMDLP LRAEDIILAG DSAGGHLVGS LLAHMAKTSP YAAPLDINGG
RFRAVLFVSP WTTMKVDQGS YETNAEKDYI NRTGVSWLKG LWIPTEEDVW ADLCEGEGAE
DVWSQVFPSP KGSPGLVKNA MVTAGTAEVL LDSCRRFARD CVRAQTVAGR RETDWSVLDG
KDFIFVECEG EIHVQPALDA ALRYHDGVTM RAILRWLENV
//
