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Database: UniProt
Entry: A6RFK2_AJECN
LinkDB: A6RFK2_AJECN
Original site: A6RFK2_AJECN 
ID   A6RFK2_AJECN            Unreviewed;       346 AA.
AC   A6RFK2;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   16-JAN-2019, entry version 41.
DE   SubName: Full=Uracil permease {ECO:0000313|EMBL:EDN04756.1};
GN   ORFNames=HCAG_08418 {ECO:0000313|EMBL:EDN04756.1};
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=339724 {ECO:0000313|EMBL:EDN04756.1, ECO:0000313|Proteomes:UP000009297};
RN   [1] {ECO:0000313|Proteomes:UP000009297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24 {ECO:0000313|Proteomes:UP000009297};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J.,
RA   Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E.,
RA   Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M.,
RA   Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N., Orbach M.J.,
RA   Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens
RT   Coccidioides and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
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DR   EMBL; CH476665; EDN04756.1; -; Genomic_DNA.
DR   RefSeq; XP_001536636.1; XM_001536586.1.
DR   STRING; 339724.XP_001536636.1; -.
DR   EnsemblFungi; EDN04756; EDN04756; HCAG_08418.
DR   GeneID; 5443053; -.
DR   KEGG; aje:HCAG_08418; -.
DR   EuPathDB; FungiDB:HCAG_08418; -.
DR   eggNOG; KOG2466; Eukaryota.
DR   eggNOG; COG1953; LUCA.
DR   KO; K03457; -.
DR   OrthoDB; 479382at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.4160.10; -; 1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR038271; Pur-cyt_permease_sf.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000009297};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009297};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      5     24       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     44     64       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     84    109       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    133    153       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    174    192       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    198    222       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    243    271       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   346 AA;  37469 MW;  90E8BD867D1D4DA8 CRC64;
     MACIWYGVQS WIGAGIVFLA WSVHRAGGLG PVVDQRHTLQ GSKLAWAVIR GVMSSIANFA
     TLIVNSLDFS RVARKPKDAL YSQLFTIPIS FAITSFIGII VSSSSGVLYE KPVWNPLELL
     GRFLDGASKG ERFGVFIIST AFALAQLGTN ISANSISAGT DMAALFPRFL SIRRGGYICA
     AVGFAMCPWH LLSTSNNFTT YLSAYSVFLS SIAGPMICDY YLVRKGYIKV NELYSSRKHS
     PYYYTFGFSW HAYASYVSGI LINIVGFIGA IDVAGLAIPA TSKTWNEIDA DVTNLSVAYN
     QGSYESIPAS NIDEESQSRT PSSAAYDEPD SVAKGGKGHV DFLSFS
//
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