ID A6SZS9_JANMA Unreviewed; 694 AA.
AC A6SZS9;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:ABR88481.1};
GN OrderedLocusNames=mma_2086 {ECO:0000313|EMBL:ABR88481.1};
OS Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Janthinobacterium.
OX NCBI_TaxID=375286 {ECO:0000313|EMBL:ABR88481.1, ECO:0000313|Proteomes:UP000006388};
RN [1] {ECO:0000313|EMBL:ABR88481.1, ECO:0000313|Proteomes:UP000006388}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Marseille {ECO:0000313|EMBL:ABR88481.1,
RC ECO:0000313|Proteomes:UP000006388};
RX PubMed=17722982; DOI=10.1371/journal.pgen.0030138;
RA Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D.,
RA Drancourt M.;
RT "Genome analysis of Minibacterium massiliensis highlights the convergent
RT evolution of water-living bacteria.";
RL PLoS Genet. 3:1454-1463(2007).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CP000269; ABR88481.1; -; Genomic_DNA.
DR RefSeq; WP_012079939.1; NC_009659.1.
DR AlphaFoldDB; A6SZS9; -.
DR STRING; 375286.mma_2086; -.
DR KEGG; mms:mma_2086; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_4; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000006388; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:ABR88481.1};
KW Cilium {ECO:0000313|EMBL:ABR88481.1};
KW Flagellum {ECO:0000313|EMBL:ABR88481.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000006388};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 18..36
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 113..136
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 205..227
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 247..269
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 694 AA; 73997 MW; 9EEC44BCC662E801 CRC64;
MNSLKLPAWM TGQGSRAVAA PLIIIMMLSM MVLPLPAIVL DIFFSFNIAL SIIVLLTALY
TVKPLDFMVF PTVLLVSTML RLSLNVASTR VVLTEGHNGP DAAGKVIEAF GHFLIGGNYT
VGIVVFVILT IINFTVVTKG AGRIAEVGAR FALDAMPGKQ MAIDADLNAG LIGEQDARLR
RTQVAQEAEF YGAMDGASKY VRGDAIAGII VTVINVVGGL VVGMVQHDMG FSAALENYTL
LAIGDGLVAQ IPSLIISTAA GIVVSRVASE QDIGGQLVGQ LFARPQVLYI TAAIIGGMGL
IPGMPHVSFL FLASLMAGAA YLISQRNLKA PEVEPEVTAP PPAPEVEEAT WQDIVQVDTL
GLEVGYRLIP LVDKSQSGEL LRRIKGIRKK FAQEVGFLSP PVHIRDNLEL KPSAYRITLK
GVEVGSGEAL AGQFLAINPG MVSGTLPGPT TSDPAFGLPA TWIDSSMREQ AQGMGYTVVD
AGTVVATHLN HLITTHAAEL LGRQEVQQLL DHLTKESPKL VEDLVPKLIP LSTLQKVLQN
LLIEGVHIRD MHTIIETMTE HAAYIQDVNE LTALVRVALG RAIVQQLFPS TNELSVMTLD
NRLERLLTQA LQGSGPDGAG IEPGLADTIA AQAEAATRQQ ESLGLTPVLL VPAQLRALLA
RFLRRALPQL KVLSHAEVPD SKTIRVTSLV GGQV
//
