ID A6T101_JANMA Unreviewed; 509 AA.
AC A6T101;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Xanthine permease (NSC2 family) {ECO:0000313|EMBL:ABR89280.1};
GN Name=pbuX6 {ECO:0000313|EMBL:ABR89280.1};
GN OrderedLocusNames=mma_2508 {ECO:0000313|EMBL:ABR89280.1};
OS Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Janthinobacterium.
OX NCBI_TaxID=375286 {ECO:0000313|EMBL:ABR89280.1, ECO:0000313|Proteomes:UP000006388};
RN [1] {ECO:0000313|EMBL:ABR89280.1, ECO:0000313|Proteomes:UP000006388}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Marseille {ECO:0000313|EMBL:ABR89280.1,
RC ECO:0000313|Proteomes:UP000006388};
RX PubMed=17722982; DOI=10.1371/journal.pgen.0030138;
RA Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D.,
RA Drancourt M.;
RT "Genome analysis of Minibacterium massiliensis highlights the convergent
RT evolution of water-living bacteria.";
RL PLoS Genet. 3:1454-1463(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CP000269; ABR89280.1; -; Genomic_DNA.
DR AlphaFoldDB; A6T101; -.
DR STRING; 375286.mma_2508; -.
DR KEGG; mms:mma_2508; -.
DR eggNOG; COG2233; Bacteria.
DR HOGENOM; CLU_017959_8_2_4; -.
DR Proteomes; UP000006388; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 2.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006388};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 36..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 509 AA; 53445 MW; C3C954628774870C CRC64;
MNDYAKPAAS LPCIPDAGMS AQEDHPVNER LPTSKLTVLG LQHVLVMYVG AVAIPLIVGR
ALKLSPEQVA LLISADLFCC GVVSIIQSFG MTQWFGLRLP TMMGVSFVSV GPMVAIANSN
PGETGAQLLF GSIIASGFIA MLIAPVISRL LRYFPPVVTG TIILVVGITL MRVGINWIFG
NPFGPTAPSI VNPEHAKWLA EASAAQGVPA VPKGLALAPS VPNPNYAVLG GIGISALVMV
SILFIARFAK GFLGNIAVLL GIVVGGVVAT AFGMMNFDKV AKAPMFELIK PFAFGMPIFD
PILIVTFTLV MIVIMVESVG MFFALADICG IKLERKVMSA GLRTDGLGTV IGGIFNTFPY
TSFSQNIGLI GVTGVRSRFV CVAGGVILII LGFLPKVAAL VESVPTFVLG GAGLVMFGMV
IATGIRMLSG VDFKTNRNNL FVVAISVGMG MIPLIAPNFK QWMPHSIHLL IESGILLAAV
SALLLNMYFN GSKEDLAASI TAAKQADTH
//
