ID A6T1J3_JANMA Unreviewed; 473 AA.
AC A6T1J3;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Methyltransferase {ECO:0000256|RuleBase:RU362026};
DE EC=2.1.1.- {ECO:0000256|RuleBase:RU362026};
GN OrderedLocusNames=mma_2700 {ECO:0000313|EMBL:ABR90468.1};
OS Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Janthinobacterium.
OX NCBI_TaxID=375286 {ECO:0000313|EMBL:ABR90468.1, ECO:0000313|Proteomes:UP000006388};
RN [1] {ECO:0000313|EMBL:ABR90468.1, ECO:0000313|Proteomes:UP000006388}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Marseille {ECO:0000313|EMBL:ABR90468.1,
RC ECO:0000313|Proteomes:UP000006388};
RX PubMed=17722982; DOI=10.1371/journal.pgen.0030138;
RA Audic S., Robert C., Campagna B., Parinello H., Claverie J.-M., Raoult D.,
RA Drancourt M.;
RT "Genome analysis of Minibacterium massiliensis highlights the convergent
RT evolution of water-living bacteria.";
RL PLoS Genet. 3:1454-1463(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-
CC methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:16857, Rhea:RHEA-COMP:11369, Rhea:RHEA-COMP:13674,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:85452, ChEBI:CHEBI:137933; EC=2.1.1.113;
CC Evidence={ECO:0000256|ARBA:ARBA00001893};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family. N(4)
CC subfamily. {ECO:0000256|ARBA:ARBA00010203}.
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DR EMBL; CP000269; ABR90468.1; -; Genomic_DNA.
DR AlphaFoldDB; A6T1J3; -.
DR STRING; 375286.mma_2700; -.
DR REBASE; 15788; M1.JspMORF2700P.
DR KEGG; mms:mma_2700; -.
DR eggNOG; COG0863; Bacteria.
DR eggNOG; COG1475; Bacteria.
DR HOGENOM; CLU_024927_0_0_4; -.
DR Proteomes; UP000006388; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0015667; F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity; IEA:UniProtKB-EC.
DR CDD; cd16403; ParB_N_like_MT; 1.
DR Gene3D; 3.90.1530.10; Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR015840; DNA_MeTrfase_ParB.
DR InterPro; IPR017985; MeTrfase_CN4_CS.
DR InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33375; CHROMOSOME-PARTITIONING PROTEIN PARB-RELATED; 1.
DR PANTHER; PTHR33375:SF1; CHROMOSOME-PARTITIONING PROTEIN PARB-RELATED; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR Pfam; PF02195; ParBc; 1.
DR PIRSF; PIRSF036758; Aden_M_ParB; 2.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SMART; SM00470; ParB; 1.
DR SUPFAM; SSF110849; ParB/Sulfiredoxin; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00093; N4_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ABR90468.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006388};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 5..91
FT /note="ParB/Sulfiredoxin"
FT /evidence="ECO:0000259|SMART:SM00470"
FT REGION 133..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..156
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 51633 MW; AF92819A74D26EB4 CRC64;
MLNVEYRKVE ALIPYARNPR THNDEQVAKI AASIVEYGWT NPVLVDGDNG IIAGHGRLAA
AHKLGLTEVP VIELAHLSPT QKRAYVISDN RLALDAGWDD AMLALELAEL SEAGFDLALT
GFEDAEIEAL LADDLGDGDG DGDQEQDTDE PDAADDVPDT PTSPVSRSRD VWALGQHRLI
CGDAADPSVI ASLMRGEQAK LCFTSPPYGN QRDYASGGIT DWDGLMRGVF GNVPMAEDAQ
VLVNLGLIHR DNEVIPYWDG WLGWMRTQGW RRFAWYVWDQ GPGMPGDWQG RLAPSFEFVF
HFNRQNRKPN KIVPCKHAGQ DSHLRADGSS TAMRGKDGEV GGWTHAGQPT QDKRIPDSVI
RVMRHKGKIG QDIDHPAVFP VALPEFILDA YSDSGDIVFE PFGGSGTTML AAERTGRRCR
AVEIAPEYVD VAVKRFQQNF PDVPVTLLGD GENVGQTFKA VAAERLAGAA VSP
//
