ID   A6T5C5_KLEP7            Unreviewed;       605 AA.
AC   A6T5C5;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=Maltodextrin glucosidase {ECO:0000313|EMBL:ABR75796.1};
GN   Name=malZ {ECO:0000313|EMBL:ABR75796.1};
GN   ORFNames=KPN_00344 {ECO:0000313|EMBL:ABR75796.1};
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=272620 {ECO:0000313|EMBL:ABR75796.1, ECO:0000313|Proteomes:UP000000265};
RN   [1] {ECO:0000313|EMBL:ABR75796.1, ECO:0000313|Proteomes:UP000000265}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [2] {ECO:0000313|EMBL:ABR75796.1, ECO:0000313|Proteomes:UP000000265}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|ARBA:ARBA00008061}.
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DR   EMBL; CP000647; ABR75796.1; -; Genomic_DNA.
DR   RefSeq; WP_004147293.1; NC_009648.1.
DR   AlphaFoldDB; A6T5C5; -.
DR   STRING; 272620.KPN_00344; -.
DR   CAZy; CBM34; Carbohydrate-Binding Module Family 34.
DR   CAZy; GH13; Glycoside Hydrolase Family 13.
DR   PaxDb; 272620-KPN_00344; -.
DR   EnsemblBacteria; ABR75796; ABR75796; KPN_00344.
DR   KEGG; kpn:KPN_00344; -.
DR   HOGENOM; CLU_006462_6_4_6; -.
DR   Proteomes; UP000000265; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004558; F:alpha-1,4-glucosidase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd11338; AmyAc_CMD; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR017069; MalZ.
DR   PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR10357:SF210; MALTODEXTRIN GLUCOSIDASE; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   PIRSF; PIRSF036918; Maltodextrin_glucosidase; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   3: Inferred from homology;
FT   DOMAIN          127..521
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
FT   ACT_SITE        336
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036918-50"
FT   ACT_SITE        373
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036918-50"
FT   SITE            448
FT                   /note="Transition state stabilizer"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036918-51"
SQ   SEQUENCE   605 AA;  68521 MW;  43FEB7AEA2038918 CRC64;
     MLKAWHLPVA PFIKVQQDRL FITLWLSGES LPQRITLRAE EDNEELSLPM QRLRQAPQPG
     VVAWRGEISL ASGQPRRRYS FKLLWADHQR WFTPQGFTRF PPARLEQFAI DLPDAGPQWV
     ADQVFYQIFP DRFARSAARD ADQDAVYYHH AAGREIVRKA WDDPLTGEAG GSTFYGGDLD
     GISEKLPYLK QLGVTALYLN PVFAAPSVHK YDTEDYRRVD PQFGGDAALL RLRHNTQRAG
     MRMILDGVFN HTGDSHPWFD RHQQGSGGAG HDPDSPWRDW FTFSEEGQAH NWLGYASLPK
     LDYRSTSLVN EIYAGEDSIV RHWLKAPWSM DGWRLDVVHM LGEGGGARNN LQHIAGITQA
     AKQAQPEAFV FGEHFGDARQ WLQADAEDAA MNYRGFTFPI WGFLANTDIS YDPQKIDAQT
     CMAWMDNYRA GLSHQQQLRM FNQLDSHDTA RFKSLLGKDV ARLPLAVVWL FSWPGVPCIY
     YGDEVGVDGN NDPFCRKPFP WDPALQDTQL LALYQRMAKL RKAHQALRYG GCQVIYAEDN
     VVVFVRVYKQ QRVLVAINRG EACEVVIEDS PLLNVAGWTL QEGAGAFQDG VLTLPAISAN
     VWSGR
//