ID A6T5I4_KLEP7 Unreviewed; 624 AA.
AC A6T5I4;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Periplasmic chaperone PpiD {ECO:0000256|ARBA:ARBA00040743};
DE AltName: Full=Periplasmic folding chaperone {ECO:0000256|ARBA:ARBA00042775};
GN Name=ppiD {ECO:0000313|EMBL:ABR75855.1};
GN ORFNames=KPN_00403 {ECO:0000313|EMBL:ABR75855.1};
OS Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=272620 {ECO:0000313|EMBL:ABR75855.1, ECO:0000313|Proteomes:UP000000265};
RN [1] {ECO:0000313|EMBL:ABR75855.1, ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2] {ECO:0000313|EMBL:ABR75855.1, ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RG The Klebsiella pneumonia Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004382}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004382}; Periplasmic side
CC {ECO:0000256|ARBA:ARBA00004382}.
CC -!- SIMILARITY: Belongs to the PpiD chaperone family.
CC {ECO:0000256|ARBA:ARBA00038408}.
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DR EMBL; CP000647; ABR75855.1; -; Genomic_DNA.
DR RefSeq; WP_004177252.1; NC_009648.1.
DR AlphaFoldDB; A6T5I4; -.
DR STRING; 272620.KPN_00403; -.
DR jPOST; A6T5I4; -.
DR PaxDb; 272620-KPN_00403; -.
DR EnsemblBacteria; ABR75855; ABR75855; KPN_00403.
DR KEGG; kpn:KPN_00403; -.
DR HOGENOM; CLU_023843_1_1_6; -.
DR Proteomes; UP000000265; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.40; -; 1.
DR Gene3D; 1.10.4030.10; Porin chaperone SurA, peptide-binding domain; 1.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR000297; PPIase_PpiC.
DR InterPro; IPR023058; PPIase_PpiC_CS.
DR InterPro; IPR027304; Trigger_fact/SurA_dom_sf.
DR PANTHER; PTHR47529; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D; 1.
DR PANTHER; PTHR47529:SF1; PERIPLASMIC CHAPERONE PPID; 1.
DR Pfam; PF13145; Rotamase_2; 1.
DR Pfam; PF13624; SurA_N_3; 1.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR SUPFAM; SSF109998; Triger factor/SurA peptide-binding domain-like; 1.
DR PROSITE; PS01096; PPIC_PPIASE_1; 1.
DR PROSITE; PS50198; PPIC_PPIASE_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Isomerase {ECO:0000256|PROSITE-ProRule:PRU00278,
KW ECO:0000313|EMBL:ABR75855.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Rotamase {ECO:0000256|PROSITE-ProRule:PRU00278};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 266..355
FT /note="PpiC"
FT /evidence="ECO:0000259|PROSITE:PS50198"
SQ SEQUENCE 624 AA; 67835 MW; 7C2A4C6C76D87F23 CRC64;
MMDNLRTAAN SVVLKIIFGI IIVSFILTGV SGYLIGGGKN YAAKVNGQEI GRGQFENAVA
SERNRMQQQL GDQFSELAAN ENYMKTMRQQ VLNRLIDESL LDQYARELGL SISDEQVKQA
IFQTQAFQTN GKFDNQRFSG IVAQMGMTTD QYAQALRNQL TTQQLINAIA GTDFMLPGES
DQLAALVSQQ RVVREATINV NALAAKQTAS DEEINAFWQQ NQARFMAPEQ FRVSYIKMDA
ASMQESASDE EIQSWYDQHK DQFTQPQRNR YSVIQTKTEA DAKAVLAELQ KGADFATLAK
EKSTDIISAR NGGDMGWMED ASTVPELKDA GLKEKGQLSG VIKSSVGFLV ARLDDVQPAQ
VKPLADVRND IAAKVKQEKA LDAYYALQQK VSDAASNDNE SLASAAQVAG LKVVETGWFG
RDNLPEELNF KPVADAIFNG GLVGENGAPG SNSDIITVDG DRAFVLRISE HKAEAVKPLA
EVKAQVSDIV KHNKAEQQAK LEADKLLAAL KDGKGDEAMK AAGLSFGAPQ TLSRTGQDPL
SQLAFTLPLP QQGKPVYGVG SNMQGDVVLV ALDEVKAGSM PEEQKKAMVQ GITQNNAQIA
FEALMSNLRK AAKIKLGDSI DQQQ
//
