ID A6T5Z7_KLEP7 Unreviewed; 336 AA.
AC A6T5Z7;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE RecName: Full=ABC-type dipeptide transporter {ECO:0000256|ARBA:ARBA00038852};
DE EC=7.4.2.9 {ECO:0000256|ARBA:ARBA00038852};
GN ORFNames=KPN_00568 {ECO:0000313|EMBL:ABR76018.1};
OS Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=272620 {ECO:0000313|EMBL:ABR76018.1, ECO:0000313|Proteomes:UP000000265};
RN [1] {ECO:0000313|EMBL:ABR76018.1, ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2] {ECO:0000313|EMBL:ABR76018.1, ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RG The Klebsiella pneumonia Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a dipeptide(out) + ATP + H2O = a dipeptide(in) + ADP + H(+) +
CC phosphate; Xref=Rhea:RHEA:23120, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:90799, ChEBI:CHEBI:456216; EC=7.4.2.9;
CC Evidence={ECO:0000256|ARBA:ARBA00036951};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004417}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004417}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC {ECO:0000256|ARBA:ARBA00005417}.
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DR EMBL; CP000647; ABR76018.1; -; Genomic_DNA.
DR RefSeq; WP_004191439.1; NC_009648.1.
DR AlphaFoldDB; A6T5Z7; -.
DR STRING; 272620.KPN_00568; -.
DR PaxDb; 272620-KPN_00568; -.
DR EnsemblBacteria; ABR76018; ABR76018; KPN_00568.
DR KEGG; kpn:KPN_00568; -.
DR HOGENOM; CLU_000604_1_23_6; -.
DR Proteomes; UP000000265; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0015833; P:peptide transport; IEA:InterPro.
DR CDD; cd03257; ABC_NikE_OppD_transporters; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013563; Oligopep_ABC_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01727; oligo_HPY; 1.
DR PANTHER; PTHR43297:SF6; DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DPPD; 1.
DR PANTHER; PTHR43297; OLIGOPEPTIDE TRANSPORT ATP-BINDING PROTEIN APPD; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF08352; oligo_HPY; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:ABR76018.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 7..257
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 336 AA; 37013 MW; 90C5B45D017B08F5 CRC64;
MSDNAFVHVR DLRVVFRRDG QTINAVNGVS FEVQKGEVMA LIGESGSGKS VTLRALMRLH
PPGSSELSGT LQVGDDEVLT MSASQLRRYR GGRCAMIFQE PLLAFDPVYT VGQQIIEGLR
RHEGLSRQAA RDRALEALRQ VRIPSPERRL DAYPHEMSGG MRQRAMIALA LSCNPQLLLA
DEPTTALDAT VQIQILILLR EQQKQRGLSI VFVTHDIGAA VEIADRVAVM YAGRIVEEAS
MSEILRHPRH PYTQVLLGSR PKEGLKKGDA LHCIPGAPPD LARLPPGCAF AERCPHRRPV
CEQSLPPTES VAERHAVSCH RWRELAIDAN AQALAV
//
