ID A6TBA2_KLEP7 Unreviewed; 595 AA.
AC A6TBA2;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Diguanylate cyclase/cyclic diguanylate phosphodiesterase {ECO:0008006|Google:ProtNLM};
GN ORFNames=KPN_02455 {ECO:0000313|EMBL:ABR77873.1};
OS Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=272620 {ECO:0000313|EMBL:ABR77873.1, ECO:0000313|Proteomes:UP000000265};
RN [1] {ECO:0000313|EMBL:ABR77873.1, ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2] {ECO:0000313|EMBL:ABR77873.1, ECO:0000313|Proteomes:UP000000265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RG The Klebsiella pneumonia Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000647; ABR77873.1; -; Genomic_DNA.
DR AlphaFoldDB; A6TBA2; -.
DR STRING; 272620.KPN_02455; -.
DR PaxDb; 272620-KPN_02455; -.
DR EnsemblBacteria; ABR77873; ABR77873; KPN_02455.
DR KEGG; kpn:KPN_02455; -.
DR HOGENOM; CLU_000445_70_50_6; -.
DR Proteomes; UP000000265; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 125..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 215..346
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 355..595
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 595 AA; 67498 MW; B02E0B315039BA76 CRC64;
MSQMVSEYMR LESRLAGMAI GAEGADHDEV RLRLEIMMSQ IELLQEGDLG KFINKSEQRK
TVVATLIRNL HLLDKQVDTM TPEQVRQILP VLSELDGPLT SMAAATLMQD INIVNITHDK
IQHLYYIYSV ISILLIAMCI TLGLLMLRQN NNLRRAHVRM KTLANDLQAS KEKLQVQNRR
LQYDAYHDSL TGMPNRLSFW QRLQEIVNQV RPYKGCAVVM LFDLDSFKDV NDTLGHDAGD
KLLQDLASRL SFFRKTSETL YRLGGDEFAM LSYDLTEEMA LERANIIREK ISQPYQIYDA
QINIDACIGI VISDGESRTD YLYKCADLAL YEAKKEGSGH VQIFRPGMLQ RLQENKSFED
DLLQALAHDE FKVYYQPIAD TVTREIYGYE ALVRWFHPVR GAVPPTVFIP VAEKIGLINA
LGEWVLKTAC AEAASWATPL KVSVNVSPIQ LMNTSLTDTI IEVLHQTGLD PRRLDLEITE
SDVFNENTRS LEILSQLREL GIQISIDDFG TGYSSLSRLS YFPFDKIKID RSFVINIPEQ
KDDLDIVRLI ISMGKSLHMR IVAEGVETEE QLASLQALGC DLVQGYLIGK PSPLR
//
