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Database: UniProt
Entry: A6TIJ2_KLEP7
LinkDB: A6TIJ2_KLEP7
Original site: A6TIJ2_KLEP7 
ID   A6TIJ2_KLEP7            Unreviewed;      1753 AA.
AC   A6TIJ2;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   07-OCT-2020, entry version 78.
DE   SubName: Full=OriT nicking-unwinding {ECO:0000313|EMBL:ABR80415.1};
GN   Name=traI {ECO:0000313|EMBL:ABR80415.1};
GN   ORFNames=KPN_pKPN3p06036 {ECO:0000313|EMBL:ABR80415.1},
GN   KPN_pKPN4p07159 {ECO:0000313|EMBL:ABR80538.1};
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OG   Plasmid pKPN3 {ECO:0000313|EMBL:ABR80415.1,
OG   ECO:0000313|Proteomes:UP000000265}, and
OG   Plasmid pKPN4 {ECO:0000313|EMBL:ABR80538.1,
OG   ECO:0000313|Proteomes:UP000000265}.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=272620 {ECO:0000313|EMBL:ABR80415.1, ECO:0000313|Proteomes:UP000000265};
RN   [1] {ECO:0000313|EMBL:ABR80538.1, ECO:0000313|Proteomes:UP000000265}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 {ECO:0000313|EMBL:ABR80538.1}, and ATCC 700721 /
RC   MGH 78578 {ECO:0000313|Proteomes:UP000000265};
RC   PLASMID=pKPN3 {ECO:0000313|Proteomes:UP000000265}, and pKPN4
RC   {ECO:0000313|EMBL:ABR80538.1, ECO:0000313|Proteomes:UP000000265};
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABR80415.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 700721 {ECO:0000313|EMBL:ABR80415.1};
RC   PLASMID=pKPN3 {ECO:0000313|EMBL:ABR80415.1};
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000648; ABR80415.1; -; Genomic_DNA.
DR   EMBL; CP000649; ABR80538.1; -; Genomic_DNA.
DR   RefSeq; WP_004153029.1; NC_009650.1.
DR   DNASU; 5343231; -.
DR   EnsemblBacteria; ABR80415; ABR80415; KPN_pKPN3p06036.
DR   EnsemblBacteria; ABR80538; ABR80538; KPN_pKPN4p07159.
DR   KEGG; kpn:KPN_pKPN3p06036; -.
DR   KEGG; kpn:KPN_pKPN4p07159; -.
DR   HOGENOM; CLU_001748_2_1_6; -.
DR   OMA; STWETHR; -.
DR   BioCyc; KPNE272620:G1G8J-5439-MONOMER; -.
DR   BioCyc; KPNE272620:G1G8J-5582-MONOMER; -.
DR   Proteomes; UP000000265; Plasmid pKPN3.
DR   Proteomes; UP000000265; Plasmid pKPN4.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0000746; P:conjugation; IEA:InterPro.
DR   InterPro; IPR014059; Conjug_relaxase_N.
DR   InterPro; IPR014129; Conjug_relaxase_TraI.
DR   InterPro; IPR009767; DNA_helicase_TraI.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR040668; TraI_2B.
DR   InterPro; IPR040987; TraI_N.
DR   InterPro; IPR014862; TrwC.
DR   Pfam; PF18272; ssDNA_TraI_N; 1.
DR   Pfam; PF07057; TraI; 1.
DR   Pfam; PF18340; TraI_2B; 1.
DR   Pfam; PF08751; TrwC; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR02686; relax_trwC; 1.
DR   TIGRFAMs; TIGR02760; TraI_TIGR; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Plasmid {ECO:0000313|EMBL:ABR80415.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000265}.
FT   DOMAIN          10..284
FT                   /note="TrwC"
FT                   /evidence="ECO:0000259|Pfam:PF08751"
FT   DOMAIN          577..629
FT                   /note="ssDNA_TraI_N"
FT                   /evidence="ECO:0000259|Pfam:PF18272"
FT   DOMAIN          635..714
FT                   /note="TraI_2B"
FT                   /evidence="ECO:0000259|Pfam:PF18340"
FT   DOMAIN          1433..1554
FT                   /note="TraI"
FT                   /evidence="ECO:0000259|Pfam:PF07057"
FT   REGION          1693..1715
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1229..1249
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1649..1676
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1753 AA;  190809 MW;  C0DDB2143B02E1ED CRC64;
     MMSIGSVKSA GSAGNYYTDK DNYYVIGSMD ERWQGKGAEA LGIDGKAVDK ALFTELLKGK
     LPDGSDLTRI QDGANRHRPG YDLTFSAPKS VSVMAMLGGD KRLIDAHNQA VTEAVRQLET
     LAATRVMTDG KSETVLTGNL IVAKFNHDTN RNQEPQIHTH AVVINATQNG DKWQSLGTDK
     IGKTGFIENV YANQIAFGKL YREAFKPLVE KLGYETEVVG KHGMWEMKGV PVEPFSTRSQ
     EVREAAGPDA SLKSRDVAAL DTRKSKEAID PAEKMVEWMN TLKETGFDIR GYREAADARA
     AELARAPAAP VNTDGPDITD VVTKAIAGLS DRKVQFTYAD LLARTVGQLE AKDGVFDLAR
     KGIDAAIERE QLIPLDREKG LFTSNIHVLD ELAVKALSQE VQRQNHVSVT PDASVVRQVP
     FSDAVSVLAQ DRLVMGIVSG QGGATGQRER VAELTLMARE QGRDVHILAA DNRSRDFLAG
     DVRLAGETVT GKSALQDGTA FIPGGTLIVD QAEKLSLKET ISLLDGAMRH NVQVLLSDSG
     KRSGTGSALT VLKDSGVNTY RWQGGQQTTA DIISEPDKGA RYSRLAQEFA VSVREGQESV
     AQISGTREQS VLNGLIRDSL RQEGVLGEKD TTITALTPVW LDSKSRGVRD YYREGMVMER
     WDPENRTHDR FVIDRVTASS NMLTLKDRDG VRLDLKVSAV DSQWTLFRAE TLPVAEGERL
     AVLGKIPDTR LKGGESITVM KVEEGQLTVQ RPGQKTTQTL AVGAGVFDGI KIGHGWVESP
     GRSVSETATV FASVTQRELD NATLNQLAQS GSHLRLYSAQ DAARTTEKLS RHTAFSVVSE
     QLKSRSGETD LDAAIAQQKA GLHTPAEQAI HLAIPLLESQ DLTFSRPQLL ATAMETGGGK
     VSMADIDTTI QAQIRSGQLL NVPVAHGYGN DLLISRQTWD AEKSILTHVL EGKDAVAPLM
     DRVPASLMTD LTAGQRAATR MILESTDRFT VVQGYAGVGK TTQFRAVMSA ISLLPEETRP
     RVIGLAPTHR AVGEMQSAGV DARTTASFLH DTQLLQRNGQ TPDFSNTLFL LDESSMVGLA
     DMAKAHSLIV AGGGRAVSSG DNDQLQPIAP GQPFRLMQQR SAADVAIMKE IVRQMPELRP
     AVYSLIERDV HRALTTIEQV TPEQVPRKEG AWAPGSSVVE FTPKQEKAIE KALSEGKTLP
     EGQPATLYEA LVKDYTGRTP EAQSQTLVIT HLNKDRRALN SLIHDARREN GETGKEEITL
     PVLVTSNIRD GELRKLSTWT AHKEAVALVD NVYHRISKVD KDNQLITLTD SEGKERFISP
     REASAEGVTL YRQEKITVSQ GDRMRFSKSD PERGYVANSI WEVQSVSGDS VTLSDGKITR
     TLTPKAEQAQ QHIDLAYAIT AHGAQGASEP YAIALEGVAG GREQMASFES AYVALSRMKQ
     HVQVYTDNRE GWIKAIKNSP EKATAHDILE PRNDRAVKTA DLLFGRARPL DETAAGRAAL
     QQSGLAQGSS PGKFISPGKK YPQPHVALPA FDKNGKAAGI WLSPLTDRDG RLEAIGGEGR
     IMGNEDARFV ALQNSRNGES LLAGNMGEGV RMARDNPDTG VVVRLAGDDR PWNPGAMTGG
     RVWAEPAPVA PVPQAGADII LPPEVLAQRA AEEQQRREME KKAEQTAREM AGEARKAGEP
     ADRVKEVIGD VIRGLERDRP GTEKTTLPDD PQFRRQEEAI QQVASERLQR ERLQAVERDM
     VRDLNREKTL GGD
//
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