ID   A6TUV4_ALKMQ            Unreviewed;       754 AA.
AC   A6TUV4;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Fumarate reductase/succinate dehydrogenase flavoprotein domain protein {ECO:0000313|EMBL:ABR49972.1};
GN   OrderedLocusNames=Amet_3859 {ECO:0000313|EMBL:ABR49972.1};
OS   Alkaliphilus metalliredigens (strain QYMF).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Alkaliphilus.
OX   NCBI_TaxID=293826 {ECO:0000313|EMBL:ABR49972.1, ECO:0000313|Proteomes:UP000001572};
RN   [1] {ECO:0000313|Proteomes:UP000001572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=QYMF {ECO:0000313|Proteomes:UP000001572};
RX   PubMed=27811105; DOI=10.1128/genomeA.01226-16;
RA   Hwang C., Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina Del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F.,
RA   Land M.L., Hauser L., Kyrpides N., Mikhailova N., Ye Q., Zhou J.,
RA   Richardson P., Fields M.W.;
RT   "Complete genome sequence of Alkaliphilus metalliredigens strain QYMF, an
RT   alkaliphilic and metal-reducing bacterium isolated from borax-contaminated
RT   leachate ponds.";
RL   Genome Announc. 4:0-0(2016).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000256|ARBA:ARBA00001917};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000724; ABR49972.1; -; Genomic_DNA.
DR   RefSeq; WP_012064927.1; NC_009633.1.
DR   AlphaFoldDB; A6TUV4; -.
DR   STRING; 293826.Amet_3859; -.
DR   KEGG; amt:Amet_3859; -.
DR   eggNOG; COG1053; Bacteria.
DR   eggNOG; COG3976; Bacteria.
DR   eggNOG; COG4939; Bacteria.
DR   HOGENOM; CLU_011398_4_0_9; -.
DR   OrthoDB; 3169476at2; -.
DR   Proteomes; UP000001572; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1010.20; -; 2.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR007329; FMN-bd.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   Pfam; PF04205; FMN_bind; 2.
DR   SMART; SM00900; FMN_bind; 2.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001572};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..754
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038628853"
FT   DOMAIN          48..122
FT                   /note="FMN-binding"
FT                   /evidence="ECO:0000259|SMART:SM00900"
FT   DOMAIN          146..242
FT                   /note="FMN-binding"
FT                   /evidence="ECO:0000259|SMART:SM00900"
SQ   SEQUENCE   754 AA;  80644 MW;  381C25B10051C2FE CRC64;
     MKQMQKQVVF FLITIMMVSM LVGCSQETGT SKETGSTREA TFTGVARGYG GEVEVTITFD
     EDKMISVIAI GDNETTGIGT NALEKLPEAI LETNSADVEA ISGATVTSKA IKEAAQSAIA
     QSRGEATAEL PELMMTPGTY VGQAQGYAGT LEVTVEVSEN EIISIELTDN IPQENEMIDR
     EFWAAKYPVA MLRDTPQILK TVTDRLPDRI VESQSLAVDV ISGATVSSSG FMMAVRDAIV
     QAGGNPAALN RPIEKNTAEE VYEADVVIIG GGTSGTSAVA SAKDEGASVI LIEKSGRVGG
     TGSLSSQPMT LGASIQLENN VDIMDEDELF EEWMAQNHWY VNGGTLRRFL QTTGSTVDWL
     AERGGFNWGL SPWSQHWIVD YVDDSLGSMG VADSFEQLIS DVDMVLYETT GKSLIVDSHG
     AVVGVIAEKY DGTKVTVNAK SVIIATGGML GNKDLMEQYN NGYSYEIFGL AQNIGEGFEM
     ALEAGAVEWN VGGVAAHLTD VAGRRRVGGF DIYDTSIPYT LSITPSLLKV NQRGERFMDE
     NAKAGSMNSS TNFVLANGSH NFTIVSQQQV EVLKAEGLAG IGMDTVPPGA NFFLQPLEPD
     YKMENIEAVL AAGEEIEIAY KGDTLEELAE VTGMDPATFV RNVERYNKMA EEGRDSYFNK
     PVQYMNHLGN EGPYYAIKAV PLAYSSLGGV RVDENMQALT ADGRPITGLY AVGVESIGSV
     LDGVAYPKLD GVALGWGFNS GRIGGIEAGK AALK
//