ID   A6UVC1_META3            Unreviewed;       244 AA.
AC   A6UVC1;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   RecName: Full=uroporphyrinogen-III C-methyltransferase {ECO:0000256|ARBA:ARBA00012162};
DE            EC=2.1.1.107 {ECO:0000256|ARBA:ARBA00012162};
GN   OrderedLocusNames=Maeo_0861 {ECO:0000313|EMBL:ABR56443.1};
OS   Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 /
OS   Nankai-3).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=419665 {ECO:0000313|EMBL:ABR56443.1, ECO:0000313|Proteomes:UP000001106};
RN   [1] {ECO:0000313|EMBL:ABR56443.1, ECO:0000313|Proteomes:UP000001106}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3
RC   {ECO:0000313|Proteomes:UP000001106};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A.,
RA   Sieprawska-Lupa M., Whitman W.B., Richardson P.;
RT   "Complete sequence of Methanococcus aeolicus Nankai-3.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC       {ECO:0000256|RuleBase:RU003960}.
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DR   EMBL; CP000743; ABR56443.1; -; Genomic_DNA.
DR   RefSeq; WP_011973575.1; NC_009635.1.
DR   AlphaFoldDB; A6UVC1; -.
DR   STRING; 419665.Maeo_0861; -.
DR   GeneID; 5326738; -.
DR   KEGG; mae:Maeo_0861; -.
DR   eggNOG; arCOG00644; Archaea.
DR   HOGENOM; CLU_011276_7_0_2; -.
DR   OrthoDB; 24444at2157; -.
DR   Proteomes; UP000001106; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0019354; P:siroheme biosynthetic process; IEA:InterPro.
DR   CDD; cd11642; SUMT; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR006366; CobA/CysG_C.
DR   InterPro; IPR003043; Uropor_MeTrfase_CS.
DR   NCBIfam; TIGR01469; cobA_cysG_Cterm; 1.
DR   PANTHER; PTHR45790:SF3; S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR   Pfam; PF00590; TP_methylase; 1.
DR   SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
DR   PROSITE; PS00839; SUMT_1; 1.
DR   PROSITE; PS00840; SUMT_2; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000256|RuleBase:RU003960};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003960}.
FT   DOMAIN          3..219
FT                   /note="Tetrapyrrole methylase"
FT                   /evidence="ECO:0000259|Pfam:PF00590"
SQ   SEQUENCE   244 AA;  26699 MW;  9E8B3CED6BDD757B CRC64;
     MNVFLVGAGP GDEGLITVKG LDLIKKADII IYDDLVGKNL LKYSKEDAEL IYVGKRKGKH
     SHKQEEINNI LVEKAKDAIA NNKIVVRLKG GDSFIFGRGG EEVLELKKHN IDYEMVPGIT
     SSIAVPEVSD IPLTHRKVAT SFTVVTGHEA EDKKENEKQV KLSELNANTI VILMGITNLE
     NHVMELLKNQ NRTVDTPVAI IMNGTRPDQK IIKGNLGNIV NIAKENNIAP PGIIVVGDVV
     NVLE
//