GenomeNet

Database: UniProt
Entry: A6VQ42
LinkDB: A6VQ42
Original site: A6VQ42 
ID   RNFC_ACTSZ              Reviewed;         703 AA.
AC   A6VQ42;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   16-JAN-2019, entry version 81.
DE   RecName: Full=Ion-translocating oxidoreductase complex subunit C {ECO:0000255|HAMAP-Rule:MF_00461};
DE            EC=7.-.-.- {ECO:0000255|HAMAP-Rule:MF_00461};
DE   AltName: Full=Rnf electron transport complex subunit C {ECO:0000255|HAMAP-Rule:MF_00461};
GN   Name=rnfC {ECO:0000255|HAMAP-Rule:MF_00461};
GN   OrderedLocusNames=Asuc_1737;
OS   Actinobacillus succinogenes (strain ATCC 55618 / 130Z).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=339671;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 55618 / 130Z;
RX   PubMed=21118570; DOI=10.1186/1471-2164-11-680;
RA   McKinlay J.B., Laivenieks M., Schindler B.D., McKinlay A.A.,
RA   Siddaramappa S., Challacombe J.F., Lowry S.R., Clum A., Lapidus A.L.,
RA   Burkhart K.B., Harkins V., Vieille C.;
RT   "A genomic perspective on the potential of Actinobacillus succinogenes
RT   for industrial succinate production.";
RL   BMC Genomics 11:680-680(2010).
CC   -!- FUNCTION: Part of a membrane-bound complex that couples electron
CC       transfer with translocation of ions across the membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_00461}.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00461};
CC       Note=Binds 2 [4Fe-4S] clusters per subunit. {ECO:0000255|HAMAP-
CC       Rule:MF_00461};
CC   -!- SUBUNIT: The complex is composed of six subunits: RnfA, RnfB,
CC       RnfC, RnfD, RnfE and RnfG. {ECO:0000255|HAMAP-Rule:MF_00461}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00461}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00461}.
CC   -!- SIMILARITY: Belongs to the 4Fe4S bacterial-type ferredoxin family.
CC       RnfC subfamily. {ECO:0000255|HAMAP-Rule:MF_00461}.
DR   EMBL; CP000746; ABR75089.1; -; Genomic_DNA.
DR   RefSeq; WP_012073466.1; NC_009655.1.
DR   STRING; 339671.Asuc_1737; -.
DR   PRIDE; A6VQ42; -.
DR   EnsemblBacteria; ABR75089; ABR75089; Asuc_1737.
DR   KEGG; asu:Asuc_1737; -.
DR   eggNOG; ENOG4107QTR; Bacteria.
DR   eggNOG; COG4656; LUCA.
DR   HOGENOM; HOG000279299; -.
DR   KO; K03615; -.
DR   OMA; QQLYWYS; -.
DR   OrthoDB; 688908at2; -.
DR   BioCyc; ASUC339671:G1G9D-1818-MONOMER; -.
DR   Proteomes; UP000001114; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1060.10; -; 1.
DR   Gene3D; 3.40.50.11540; -; 1.
DR   HAMAP; MF_00461; RsxC_RnfC; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR010208; Ion_transpt_RnfC/RsxC.
DR   InterPro; IPR011538; Nuo51_FMN-bd.
DR   InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR   InterPro; IPR026902; RnfC_N.
DR   InterPro; IPR019554; Soluble_ligand-bd.
DR   PANTHER; PTHR43034; PTHR43034; 1.
DR   Pfam; PF01512; Complex1_51K; 1.
DR   Pfam; PF13237; Fer4_10; 1.
DR   Pfam; PF13375; RnfC_N; 1.
DR   Pfam; PF10531; SLBB; 1.
DR   SUPFAM; SSF142019; SSF142019; 1.
DR   SUPFAM; SSF46548; SSF46548; 1.
DR   TIGRFAMs; TIGR01945; rnfC; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   3: Inferred from homology;
KW   4Fe-4S; Cell inner membrane; Cell membrane; Complete proteome;
KW   Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding;
KW   Reference proteome; Repeat; Translocase; Transport.
FT   CHAIN         1    703       Ion-translocating oxidoreductase complex
FT                                subunit C.
FT                                /FTId=PRO_1000072385.
FT   DOMAIN      369    398       4Fe-4S ferredoxin-type 1.
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   DOMAIN      408    437       4Fe-4S ferredoxin-type 2.
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       378    378       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       381    381       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       384    384       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       388    388       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       417    417       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       420    420       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       423    423       Iron-sulfur 2 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
FT   METAL       427    427       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000255|HAMAP-Rule:MF_00461}.
SQ   SEQUENCE   703 AA;  76026 MW;  28C50504264F6845 CRC64;
     MTDVLTRYNS GKLWDFDGGI HPPEMKSQSN STPISTALLA EDYYVPVKQH AGNAGNLLVK
     EGDYVLKGQP LTLGDGLRVL PVHAPTSGTV VAIEPHIAAH PSGLSELAVH IHADGKDQWR
     PQNPTEDYFT HTPERLIEKI YRAGVAGLGG AVFPTGAKVD AALGKVKLLI INGAECEPYI
     TCDDRLMRDY AAEIIEGVRI LRYILRPEKV VIAIEDNKPE AVNALRTSLQ GANDMDIRVI
     PTKYPSGAAK QLIYVLTGME VPHGQRSSSI GVLMQNVGTA FAVKRAVIND EPLIERVVTL
     TGDKIPHKGN QWVRLGTPID FILKHVGYQP DNRFPVFVGG PMMGLIVPDL RAPITKTANC
     LLAPDHFEYD PQATEQACIR CSACSDACPV HLMPQQMYWY ARAEDHEKSN QYQLMDCIEC
     GLCAYVCPSH IPLIQYFRQE KAKIWDIEAK ARKSEEAKIR FEARQARLER EEQARKARSQ
     RAAAARREEL AANKGEDPVQ AALARLKAKK AGEAPETGGS AQGAPHIKTI RTEKGQSVPD
     NSEITALRRA RRLARQQTNG NSPVSSASNS DSATISADNT HSTPKTAQNQ TAPDPKKAAV
     AVAIARAKAK KAAQTTTGET VTENVTEKTA QNPTAPDPKK AAVAAAIARA KAKKAAQATT
     GETATEKTAQ NPTAPDPKKA AVAAAIARAK AKKAAMLAES EKK
//
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