ID   A6W234_MARMS            Unreviewed;       655 AA.
AC   A6W234;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   27-MAR-2024, entry version 71.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:ABR72763.1};
GN   OrderedLocusNames=Mmwyl1_3864 {ECO:0000313|EMBL:ABR72763.1};
OS   Marinomonas sp. (strain MWYL1).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae; Marinomonas.
OX   NCBI_TaxID=400668 {ECO:0000313|EMBL:ABR72763.1};
RN   [1] {ECO:0000313|EMBL:ABR72763.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MWYL1 {ECO:0000313|EMBL:ABR72763.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y.,
RA   Richardson P.;
RT   "Complete sequence of Marinomonas sp. MWYL1.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000749; ABR72763.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6W234; -.
DR   STRING; 400668.Mmwyl1_3864; -.
DR   KEGG; mmw:Mmwyl1_3864; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_50_6; -.
DR   OrthoDB; 1316910at2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF84; SIGNALLING PROTEIN WITH EAL DOMAIN; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          258..389
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          398..651
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   655 AA;  73997 MW;  996A2D195CFC8676 CRC64;
     MTVLLELQRD KSFRLKLILV CLTVALSVAS IYTVVSYRLA ADLGLKTALD SLHRQAMLIH
     GELLITNKKA PEEHLAELIK LVYFNGHLEE SELYIKITGP NLEWSIDHKM NPIETDLLLS
     KIASLTSTSL STIDMPNGQE SIKGKQFLWQ MVRGDKYQVI IIKTSEYIDN TLTFVMKRLI
     ITSIIVFWLA TWFALTLSSW MNKRVQDKND SLAHLATHDS LTGLPNRLFL ANMMHPIIID
     HSDPTHKKYE EFYSHYPKQG CLFVIDLDKF KEVNDTFGHA AGDTLLINVA KKLGQVLDDA
     QTLVRFGGDK FIIWAPEVDI EQAKNLVQRL IITCNEPVMI NKLAISTGAS IGLSHYPSQA
     TDPESLILYA DTAMYEAKQN RSGWSMFSER NIQCGRQRLK LRADLDDALS ERQIKLHYQP
     KVSLKDGHII GVEALARWYH PTDGLLPPAH FIELIEQSGR VQEFGRYVIT NAIEQLDLWH
     QQGLFTHIAI NLSPYNLLDP SLLDFTLRLL KNHKIEANKL EIELIESATS VNIEYISQSL
     NNFKEAGIKL AIDDFGTGMS SLSYISNLNV NHIKIDRSFI DGVEQDIRKQ AVVSSVVMLA
     NSFECEVIAE GIENKSQSEM LIEIGCLYGQ GYYYAKPMTA ENMQAMLLAD AALPI
//