ID A6W3L9_MARMS Unreviewed; 259 AA.
AC A6W3L9;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=Sulfate transporter CysZ {ECO:0000256|HAMAP-Rule:MF_00468};
GN Name=cysZ {ECO:0000256|HAMAP-Rule:MF_00468};
GN OrderedLocusNames=Mmwyl1_4403 {ECO:0000313|EMBL:ABR73298.1};
OS Marinomonas sp. (strain MWYL1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=400668 {ECO:0000313|EMBL:ABR73298.1};
RN [1] {ECO:0000313|EMBL:ABR73298.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MWYL1 {ECO:0000313|EMBL:ABR73298.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA Johnston A.W.B., Todd J.D., Rogers R., Wexler M., Bond P.L., Li Y.,
RA Richardson P.;
RT "Complete sequence of Marinomonas sp. MWYL1.";
RL Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: High affinity, high specificity proton-dependent sulfate
CC transporter, which mediates sulfate uptake. Provides the sulfur source
CC for the cysteine synthesis pathway. {ECO:0000256|HAMAP-Rule:MF_00468}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_00468}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_00468}.
CC -!- SIMILARITY: Belongs to the CysZ family. {ECO:0000256|HAMAP-
CC Rule:MF_00468}.
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DR EMBL; CP000749; ABR73298.1; -; Genomic_DNA.
DR AlphaFoldDB; A6W3L9; -.
DR STRING; 400668.Mmwyl1_4403; -.
DR KEGG; mmw:Mmwyl1_4403; -.
DR eggNOG; COG2981; Bacteria.
DR HOGENOM; CLU_070331_1_0_6; -.
DR OrthoDB; 5292355at2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-UniRule.
DR GO; GO:0000103; P:sulfate assimilation; IEA:InterPro.
DR HAMAP; MF_00468; CysZ; 1.
DR InterPro; IPR022985; Sulfate_CysZ.
DR PANTHER; PTHR37468; SULFATE TRANSPORTER CYSZ; 1.
DR PANTHER; PTHR37468:SF1; SULFATE TRANSPORTER CYSZ; 1.
DR Pfam; PF07264; EI24; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|HAMAP-Rule:MF_00468};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_00468}; Cysteine biosynthesis {ECO:0000256|HAMAP-Rule:MF_00468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00468};
KW Sulfate transport {ECO:0000256|ARBA:ARBA00023032, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00468}.
FT TRANSMEM 26..50
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 70..96
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 140..159
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 205..238
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
SQ SEQUENCE 259 AA; 29362 MW; B6816644A834CDA6 CRC64;
MITHPFKAAG AFLKAFPLVF SKDLRLFILA PLLANFVLVG LLYMVAFSYF QTLMDSAMGY
LPEWVSFLNW LFYLIFAAII SVLLFYSFSV GVNILAAPFM AFLAEKVEEK ETGKVFDETL
TAGVLIAIVG RSLQREFQKI LYFLPRFILL LLLSFIPLVN VIAPVLLLLF SAWMLSLQYM
DYAFDNNKVK FHDMRMALRS KPLLCWTFGG IVMVGLTIPF FNLFVMPIAV VAATLLWISV
FRSQHGDFSA LLDRTNGTL
//
