ID A6W5Z3_KINRD Unreviewed; 373 AA.
AC A6W5Z3;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=IMP dehydrogenase family protein {ECO:0000313|EMBL:ABS02232.1};
GN OrderedLocusNames=Krad_0743 {ECO:0000313|EMBL:ABS02232.1};
OS Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216).
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Kineococcus.
OX NCBI_TaxID=266940 {ECO:0000313|EMBL:ABS02232.1, ECO:0000313|Proteomes:UP000001116};
RN [1] {ECO:0000313|Proteomes:UP000001116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-149 / DSM 14245 / SRS30216
RC {ECO:0000313|Proteomes:UP000001116};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T.,
RA Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J.,
RA Fliermans C., Richardson P.;
RT "Complete sequence of chromosome of Kineococcus radiotolerans SRS30216.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
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DR EMBL; CP000750; ABS02232.1; -; Genomic_DNA.
DR RefSeq; WP_012084920.1; NC_009664.2.
DR AlphaFoldDB; A6W5Z3; -.
DR STRING; 266940.Krad_0743; -.
DR KEGG; kra:Krad_0743; -.
DR eggNOG; COG0516; Bacteria.
DR HOGENOM; CLU_064068_0_0_11; -.
DR OrthoDB; 9805398at2; -.
DR Proteomes; UP000001116; Chromosome.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd00381; IMPDH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001116}.
FT DOMAIN 15..297
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 373 AA; 39386 MW; A1A4986403B41116 CRC64;
MQEIEIGRGK RGRRAYSFDD IAVVPSRRTR DPEDVSTAWQ IDAYHFDIPV MSAPMDSVAS
PATAVLMGKL GGLGVLDLEG LWTRYEDPEP LLAEIAALDP VVAIPRMQEM YAEPVKAELI
TSRLAEVRAA GVTVAGALSP QRTNEFWKVV VDAGVDLFVI RGTTVSAEHV SGRSEPLNLK
RFIYELDVPV VVGGAAGYTA ALHLMRTGAA GVLVGFGGGA AHTTRTVLGI HAPMASAVAD
VAAARRDYMD ESGGRYVHVI ADGGVGTSGD IVKAIACGAD AVMLGASLAR ATEAPGRGWH
WGPEAHHSVL PRGERVRVGT AAPLAEILEG PGRAADGTTN LMGALRRSMA TTGYSDLKEF
QRIEVVVSPY QPA
//
