ID A6WG04_KINRD Unreviewed; 170 AA.
AC A6WG04;
DT 21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Ferritin Dps family protein {ECO:0000313|EMBL:ABS05743.1};
GN OrderedLocusNames=Krad_4280 {ECO:0000313|EMBL:ABS05743.1};
OS Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216).
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Kineococcus.
OX NCBI_TaxID=266940 {ECO:0000313|EMBL:ABS05743.1, ECO:0000313|Proteomes:UP000001116};
RN [1] {ECO:0000313|Proteomes:UP000001116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-149 / DSM 14245 / SRS30216
RC {ECO:0000313|Proteomes:UP000001116};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N.,
RA Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T.,
RA Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Bagwell C.E., Shimkets L., Berry C.J.,
RA Fliermans C., Richardson P.;
RT "Complete sequence of chromosome of Kineococcus radiotolerans SRS30216.";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0007829|PDB:4A25}
RP X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-170 IN COMPLEX WITH MANGANESE.
RX PubMed=23396000; DOI=10.1016/J.BBAGEN.2013.02.003;
RA Ardini M., Fiorillo A., Fittipaldi M., Stefanini S., Gatteschi D.,
RA Ilari A., Chiancone E.;
RT "Kineococcus radiotolerans Dps forms a heteronuclear Mn-Fe ferroxidase
RT center that may explain the Mn-dependent protection against oxidative
RT stress.";
RL Biochim. Biophys. Acta 1830:3745-3755(2013).
CC -!- SIMILARITY: Belongs to the Dps family. {ECO:0000256|ARBA:ARBA00009497,
CC ECO:0000256|RuleBase:RU003875}.
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DR EMBL; CP000750; ABS05743.1; -; Genomic_DNA.
DR PDB; 4A25; X-ray; 2.00 A; A/B/C/D=2-170.
DR PDBsum; 4A25; -.
DR AlphaFoldDB; A6WG04; -.
DR SMR; A6WG04; -.
DR STRING; 266940.Krad_4280; -.
DR KEGG; kra:Krad_4280; -.
DR eggNOG; COG0783; Bacteria.
DR HOGENOM; CLU_098183_1_3_11; -.
DR Proteomes; UP000001116; Chromosome.
DR GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR GO; GO:0016722; F:oxidoreductase activity, acting on metal ions; IEA:InterPro.
DR CDD; cd01043; DPS; 1.
DR Gene3D; 1.20.1260.10; -; 1.
DR InterPro; IPR002177; DPS_DNA-bd.
DR InterPro; IPR023188; DPS_DNA-bd_CS.
DR InterPro; IPR012347; Ferritin-like.
DR InterPro; IPR009078; Ferritin-like_SF.
DR InterPro; IPR008331; Ferritin_DPS_dom.
DR PANTHER; PTHR42932:SF2; DNA PROTECTION DURING STARVATION PROTEIN 1; 1.
DR PANTHER; PTHR42932; GENERAL STRESS PROTEIN 20U; 1.
DR Pfam; PF00210; Ferritin; 1.
DR PIRSF; PIRSF005900; Dps; 1.
DR PRINTS; PR01346; HELNAPAPROT.
DR SUPFAM; SSF47240; Ferritin-like; 1.
DR PROSITE; PS00818; DPS_1; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:4A25}; Metal-binding {ECO:0007829|PDB:4A25};
KW Reference proteome {ECO:0000313|Proteomes:UP000001116}.
FT DOMAIN 28..162
FT /note="Ferritin/DPS protein"
FT /evidence="ECO:0000259|Pfam:PF00210"
FT BINDING 48
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:4A25"
FT BINDING 55
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:4A25"
FT BINDING 58
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="2"
FT /evidence="ECO:0007829|PDB:4A25"
FT BINDING 75
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:4A25"
FT BINDING 79
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="1"
FT /evidence="ECO:0007829|PDB:4A25"
FT BINDING 144
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /ligand_label="3"
FT /evidence="ECO:0007829|PDB:4A25"
SQ SEQUENCE 170 AA; 18627 MW; 104AD1228CEDDC38 CRC64;
MTTIHDVQTT GLTQDAVTGF DASSRLNAGL QEVLVDLTAL HLQGKQAHWN IVGENWRDLH
LQLDTLVEAA RGFSDDVAER MRAVGGVPDA RPQTVAASRI GDVGPDEIDT RACVEAIVAL
VRHTVDTIRR VHDPIDAEDP ASADLLHAIT LELEKQAWMI GSENRSPRRR
//
