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Database: UniProt
Entry: A6ZTB4
LinkDB: A6ZTB4
Original site: A6ZTB4 
ID   SET5_YEAS7              Reviewed;         526 AA.
AC   A6ZTB4;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   16-JAN-2019, entry version 33.
DE   RecName: Full=Potential protein lysine methyltransferase SET5;
DE            EC=2.1.1.-;
DE   AltName: Full=SET domain-containing protein 5;
GN   Name=SET5; ORFNames=SCY_2598;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R.,
RA   Wang X., Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S.,
RA   Li Y., Davis R.W., Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces
RT   cerevisiae strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Putative protein lysine methyltransferase that acts as a
CC       virus host factor involved in the replication of positive-strand
CC       RNA viruses like the MBV. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. Histone-lysine methyltransferase
CC       family. SET5 subfamily. {ECO:0000255|PROSITE-ProRule:PRU00190}.
DR   EMBL; AAFW02000082; EDN62445.1; -; Genomic_DNA.
DR   PRIDE; A6ZTB4; -.
DR   EnsemblFungi; EDN62445; EDN62445; SCY_2598.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Methyltransferase; Nucleus;
KW   Phosphoprotein; S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    526       Potential protein lysine
FT                                methyltransferase SET5.
FT                                /FTId=PRO_0000324475.
FT   DOMAIN      112    403       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
FT   MOD_RES     517    517       Phosphoserine.
FT                                {ECO:0000250|UniProtKB:P38890}.
SQ   SEQUENCE   526 AA;  60574 MW;  11022A6C43C22C7D CRC64;
     MTLTIKIGTL NDSDQSAVHN GTENGSDFRK ITPTEEEICD DVVLLWKEEP GTEDATIQHL
     YDRITERNQS WKLSASRFRK ILNEHHLYDT DLETVSLYKD KIHFPKALDS DAKVEVKFID
     DEHGRGLFAK RDFSKGQIIL KENKPIVYIP PLDKLFLISN GKACARCGKA LYDLTQHKIM
     VHYLDCEVCK AIWCSEKCKK AHASLHELLY HSWRSNRIDI LHAGNWKRFV NYCEKYCFTA
     AFSVGLIYGS MLLDTTGEVK EQWQKLASIS QRERIKLRDA SGIGSTFSLL NGTTVHTEEE
     SDNGTKKGVE KNIDDETVWE KCYELFCGAF PKASEEIDFE KFLTMIGTFN INQYNGQVYH
     WISFINHDCE PNAYIEQVEE HEELRLHARK PIKKGEQIRI TYVNPLHGVR LRRRELRVNW
     GFLCQCDRCQ NELSTFERVP NLEKKNADAN LGVEKIDSND NSEDGSKKST GNRKSSMREA
     QPDLKEILKN GKEFELDIPE TVDTQGNVRK TSVRFDSNVS VAVDER
//
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